Sperm granulomas: An adverse effect of vasectomy

A. M. Kwart, D. S. Coffey

Research output: Contribution to journalArticle

Abstract

Spermatic granulomas were always present 6 mth after prepubertal or postpubertal vasectomy in the rat. Neither sperm leakage at the operation nor suture material is a necessary predisposing factor in granuloma formation. These granulomas contain massive accumulations of sperm (0.8 to 1.8 billion) which may account for a considerable portion of the testicular output of sperm during this 6 mth period. This might suggest minimal reabsorption of sperm in the epididymis following vasectomy. Although granulomas were most frequently found at the site of ligation, individual granulomas were observed proximally in the vas deferens and epididymis. A spectrum of granulomatous inflammation was observed in these lesions, including the ultimate reabsorption of the sperm by histiocytic phagocytes. These lesions are discussed in relation to immunologic considerations.

Original languageEnglish (US)
Pages (from-to)416-422
Number of pages7
JournalJournal of Urology
Volume110
Issue number4
StatePublished - 1973

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Vasectomy
Granuloma
Spermatozoa
Epididymis
Vas Deferens
Phagocytes
Causality
Sutures
Ligation
Inflammation

ASJC Scopus subject areas

  • Urology

Cite this

Kwart, A. M., & Coffey, D. S. (1973). Sperm granulomas: An adverse effect of vasectomy. Journal of Urology, 110(4), 416-422.

Sperm granulomas : An adverse effect of vasectomy. / Kwart, A. M.; Coffey, D. S.

In: Journal of Urology, Vol. 110, No. 4, 1973, p. 416-422.

Research output: Contribution to journalArticle

Kwart, AM & Coffey, DS 1973, 'Sperm granulomas: An adverse effect of vasectomy', Journal of Urology, vol. 110, no. 4, pp. 416-422.
Kwart AM, Coffey DS. Sperm granulomas: An adverse effect of vasectomy. Journal of Urology. 1973;110(4):416-422.
Kwart, A. M. ; Coffey, D. S. / Sperm granulomas : An adverse effect of vasectomy. In: Journal of Urology. 1973 ; Vol. 110, No. 4. pp. 416-422.
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