Spent culture supernatant of Mycobacterium tuberculosis H37Ra improves viability of aged cultures of this strain and allows small inocula to initiate growth

Zhonghe Sun, Ying Zhang

Research output: Contribution to journalArticlepeer-review

Abstract

Spent culture supernatant from early-stationary-phase Mycobacterium tuberculosis H37Ra cultures increased the viability of bacilli from aged cultures of this strain and allowed small inocula to initiate growth in liquid culture. The resuscitation factor was acid labile and heat stable, with a mass of less than 1,375 Da.

Original languageEnglish (US)
Pages (from-to)7626-7628
Number of pages3
JournalJournal of bacteriology
Volume181
Issue number24
DOIs
StatePublished - Dec 1999
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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