SPECULAR MICROSCOPY OF IRIDOCORNEAL ENDOTHELIAL SYNDROME

Lawrence W. Hirst, Harry A. Qulgley, Walter J. Stark, N. Bruce Shields

Research output: Contribution to journalArticlepeer-review

Abstract

Clinical specular microscopic examination of 17 patients with features common to the irido‐corneal endothelial syndrome (including Chandler's syndrome, iris nevus syndrome, and essential iris atrophy) revealed pathognomonic endothelial changes and no areas of normal endothelial mosaic. Even in those patients with minimal anterior synechiae, gross central endothelial changes could be found, suggesting that the endothelial changes are primary and not secondary to the iris‐corneal adhesions. Specular microscopy of the clinically‐uninvolved contralateral eye in the patients revealed frequent endothelial‐cell pleomorphism incommensurate with the patient's age. This study also confirmed the value of the specular microscope in making qualitative endothelial observations.

Original languageEnglish (US)
Pages (from-to)139-146
Number of pages8
JournalAustralian Journal of Opthalmology
Volume8
Issue number2
DOIs
StatePublished - May 1980
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology

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