Spectro-temporal dispersion management of femtosecond pulses for fiber-optic two-photon endomicroscopy

Wenxuan Liang, Gunnsteinn Hall, Xingde Li

Research output: Contribution to journalArticle

Abstract

The emerging fiber-optic two-photon endomicroscopy technology holds a strong promise for enabling translational applications of nonlinear optical imaging. Effective femtosecond pulse dispersion management is critical for achieving high-quality imaging. Here we report systematic analyses and performance characterization of a dual-fiber spectro-temporal dispersion management scheme involving a grating pair as the pulse stretcher. Compared with conventional linear-only compensation, the grating-based spectro-temporal compensation also takes into account nonlinear effects and enhances the two-photon signal by ~3-fold as experimentally demonstrated. Numerical simulations were carried out to systematically investigate the influence of several key design parameters on the overall compensation efficacy. Furthermore, comprehensive performance comparison with an ideal grism-pair counterpart reveals that a grating-pair stretcher affords much higher power throughput and thus is preferable for portable endomicroscopy systems with limited laser source power.

Original languageEnglish (US)
Pages (from-to)22877-22893
Number of pages17
JournalOptics Express
Volume26
Issue number18
DOIs
StatePublished - Sep 3 2018

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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