Speckle reduction during all-fiber common-path optical coherence tomography of the cavernous nerves

Shahab Chitchiana, Michael Fiddya, Nathaniel M. Frieda

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Improvements in identification, imaging, and visualization of the cavernous nerves during prostate cancer surgery, which are responsible for erectile function, may improve nerve preservation and postoperative sexual potency. In this study, we use a rat prostate, ex vivo, to evaluate the feasibility of optical coherence tomography (OCT) as a diagnostic tool for real-time imaging and identification of the cavernous nerves. A novel OCT system based on an all single-mode fiber common-path interferometer-based scanning system is used for this purpose. A wavelet shrinkage denoising technique using Stein's unbiased risk estimator (SURE) algorithm to calculate a data-adaptive threshold is implemented for speckle noise reduction in the OCT image. The signal-to-noise ratio (SNR) was improved by 9 dB and the image quality metrics of the cavernous nerves also improved significantly.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7168
DOIs
StatePublished - 2009
EventOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII - San Jose, CA, United States
Duration: Jan 26 2009Jan 28 2009

Other

OtherOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII
CountryUnited States
CitySan Jose, CA
Period1/26/091/28/09

Keywords

  • Cavernous nerves
  • optical coherence tomography
  • Wavelet shrinkage denoising

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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    Chitchiana, S., Fiddya, M., & Frieda, N. M. (2009). Speckle reduction during all-fiber common-path optical coherence tomography of the cavernous nerves. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 7168). [71682N] https://doi.org/10.1117/12.807444