Speckle reduction during all-fiber common-path optical coherence tomography of the cavernous nerves

Shahab Chitchiana; Michael Fiddya; Nathaniel M. Frieda

doi:10.1117/12.807444

Speckle reduction during all-fiber common-path optical coherence tomography of the cavernous nerves

Shahab Chitchiana, Michael Fiddya, Nathaniel M. Frieda

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

Improvements in identification, imaging, and visualization of the cavernous nerves during prostate cancer surgery, which are responsible for erectile function, may improve nerve preservation and postoperative sexual potency. In this study, we use a rat prostate, ex vivo, to evaluate the feasibility of optical coherence tomography (OCT) as a diagnostic tool for real-time imaging and identification of the cavernous nerves. A novel OCT system based on an all single-mode fiber common-path interferometer-based scanning system is used for this purpose. A wavelet shrinkage denoising technique using Stein's unbiased risk estimator (SURE) algorithm to calculate a data-adaptive threshold is implemented for speckle noise reduction in the OCT image. The signal-to-noise ratio (SNR) was improved by 9 dB and the image quality metrics of the cavernous nerves also improved significantly.

Original language	English (US)
Title of host publication	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	7168
DOIs	https://doi.org/10.1117/12.807444
State	Published - 2009
Event	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII - San Jose, CA, United States Duration: Jan 26 2009 → Jan 28 2009

Other

Other	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII
Country/Territory	United States
City	San Jose, CA
Period	1/26/09 → 1/28/09

Keywords

Cavernous nerves
optical coherence tomography
Wavelet shrinkage denoising

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Electronic, Optical and Magnetic Materials
Biomaterials
Radiology Nuclear Medicine and imaging

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10.1117/12.807444

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Chitchiana, S, Fiddya, M & Frieda, NM 2009, Speckle reduction during all-fiber common-path optical coherence tomography of the cavernous nerves. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 7168, 71682N, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII, San Jose, CA, United States, 1/26/09. https://doi.org/10.1117/12.807444

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abstract = "Improvements in identification, imaging, and visualization of the cavernous nerves during prostate cancer surgery, which are responsible for erectile function, may improve nerve preservation and postoperative sexual potency. In this study, we use a rat prostate, ex vivo, to evaluate the feasibility of optical coherence tomography (OCT) as a diagnostic tool for real-time imaging and identification of the cavernous nerves. A novel OCT system based on an all single-mode fiber common-path interferometer-based scanning system is used for this purpose. A wavelet shrinkage denoising technique using Stein's unbiased risk estimator (SURE) algorithm to calculate a data-adaptive threshold is implemented for speckle noise reduction in the OCT image. The signal-to-noise ratio (SNR) was improved by 9 dB and the image quality metrics of the cavernous nerves also improved significantly.",

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AU - Chitchiana, Shahab

AU - Fiddya, Michael

AU - Frieda, Nathaniel M.

PY - 2009

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N2 - Improvements in identification, imaging, and visualization of the cavernous nerves during prostate cancer surgery, which are responsible for erectile function, may improve nerve preservation and postoperative sexual potency. In this study, we use a rat prostate, ex vivo, to evaluate the feasibility of optical coherence tomography (OCT) as a diagnostic tool for real-time imaging and identification of the cavernous nerves. A novel OCT system based on an all single-mode fiber common-path interferometer-based scanning system is used for this purpose. A wavelet shrinkage denoising technique using Stein's unbiased risk estimator (SURE) algorithm to calculate a data-adaptive threshold is implemented for speckle noise reduction in the OCT image. The signal-to-noise ratio (SNR) was improved by 9 dB and the image quality metrics of the cavernous nerves also improved significantly.

AB - Improvements in identification, imaging, and visualization of the cavernous nerves during prostate cancer surgery, which are responsible for erectile function, may improve nerve preservation and postoperative sexual potency. In this study, we use a rat prostate, ex vivo, to evaluate the feasibility of optical coherence tomography (OCT) as a diagnostic tool for real-time imaging and identification of the cavernous nerves. A novel OCT system based on an all single-mode fiber common-path interferometer-based scanning system is used for this purpose. A wavelet shrinkage denoising technique using Stein's unbiased risk estimator (SURE) algorithm to calculate a data-adaptive threshold is implemented for speckle noise reduction in the OCT image. The signal-to-noise ratio (SNR) was improved by 9 dB and the image quality metrics of the cavernous nerves also improved significantly.

KW - Cavernous nerves

KW - optical coherence tomography

KW - Wavelet shrinkage denoising

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Speckle reduction during all-fiber common-path optical coherence tomography of the cavernous nerves

Abstract

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Keywords

ASJC Scopus subject areas

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