Specific metaphase and interphase detection of the breakpoint region in 8q24 of Burkitt lymphoma cells by triple-color fluorescence in situ hybridization

T. Ried; C. Lengauer; T. Cremer; J. Wiegant; A. K. Raap; M. Van der Ploeg; P. Groitl; M. Lipp

Specific metaphase and interphase detection of the breakpoint region in 8q24 of Burkitt lymphoma cells by triple-color fluorescence in situ hybridization

T. Ried, C. Lengauer, T. Cremer, J. Wiegant, A. K. Raap, M. Van der Ploeg, P. Groitl, M. Lipp

Research output: Contribution to journal › Article › peer-review

Abstract

Triple fluorescence in situ hybridization with a plasmid DNA library from sorted human chromosomes 8 in combination with bacteriophage clones flanking the breakpoint in 8q24 of the Burkitt lymphoma cell line J1 was used for the specific delineation of this breakpoint in individual tumor cells. With this approach, tumor-specific breakpoints in translocation chromosomes can be detected at all stages of the cell cycle with high specificity.

Original language	English (US)
Pages (from-to)	69-74
Number of pages	6
Journal	Genes Chromosomes and Cancer
Volume	4
Issue number	1
State	Published - 1992
Externally published	Yes

ASJC Scopus subject areas

Cancer Research
Genetics

Cite this

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title = "Specific metaphase and interphase detection of the breakpoint region in 8q24 of Burkitt lymphoma cells by triple-color fluorescence in situ hybridization",

abstract = "Triple fluorescence in situ hybridization with a plasmid DNA library from sorted human chromosomes 8 in combination with bacteriophage clones flanking the breakpoint in 8q24 of the Burkitt lymphoma cell line J1 was used for the specific delineation of this breakpoint in individual tumor cells. With this approach, tumor-specific breakpoints in translocation chromosomes can be detected at all stages of the cell cycle with high specificity.",

author = "T. Ried and C. Lengauer and T. Cremer and J. Wiegant and Raap, {A. K.} and {Van der Ploeg}, M. and P. Groitl and M. Lipp",

year = "1992",

language = "English (US)",

volume = "4",

pages = "69--74",

journal = "Genes Chromosomes and Cancer",

issn = "1045-2257",

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T1 - Specific metaphase and interphase detection of the breakpoint region in 8q24 of Burkitt lymphoma cells by triple-color fluorescence in situ hybridization

AU - Ried, T.

AU - Lengauer, C.

AU - Cremer, T.

AU - Wiegant, J.

AU - Raap, A. K.

AU - Van der Ploeg, M.

AU - Groitl, P.

AU - Lipp, M.

PY - 1992

Y1 - 1992

N2 - Triple fluorescence in situ hybridization with a plasmid DNA library from sorted human chromosomes 8 in combination with bacteriophage clones flanking the breakpoint in 8q24 of the Burkitt lymphoma cell line J1 was used for the specific delineation of this breakpoint in individual tumor cells. With this approach, tumor-specific breakpoints in translocation chromosomes can be detected at all stages of the cell cycle with high specificity.

AB - Triple fluorescence in situ hybridization with a plasmid DNA library from sorted human chromosomes 8 in combination with bacteriophage clones flanking the breakpoint in 8q24 of the Burkitt lymphoma cell line J1 was used for the specific delineation of this breakpoint in individual tumor cells. With this approach, tumor-specific breakpoints in translocation chromosomes can be detected at all stages of the cell cycle with high specificity.

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M3 - Article

C2 - 1377011

AN - SCOPUS:0026600244

SN - 1045-2257

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JO - Genes Chromosomes and Cancer

JF - Genes Chromosomes and Cancer

IS - 1

ER -

Specific metaphase and interphase detection of the breakpoint region in 8q24 of Burkitt lymphoma cells by triple-color fluorescence in situ hybridization

Abstract

ASJC Scopus subject areas

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