Specific binding of mouse IgE with rat mast cells

W. Koenig, H. Okudaira, K. Ishizaka

Research output: Contribution to journalArticle


Evidence was obtained that the mouse IgE antibody was absorbed in vitro by rat peritoneal mast cells, but not by macrophages. A significant absorption of the antibody was observed at 0°C in the presence of EDTA, although the rate of absorption was faster at 37°C than at 0°C. Mouse IgG1 and IgG2, which combine with mouse mast cells, did not combine with rat mast cells or macrophages at 0°C nor inhibit the binding of mouse IgE with mast cells.

Original languageEnglish (US)
Pages (from-to)1652-1659
Number of pages8
JournalJournal of Immunology
Issue number5
StatePublished - Dec 1 1974

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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    Koenig, W., Okudaira, H., & Ishizaka, K. (1974). Specific binding of mouse IgE with rat mast cells. Journal of Immunology, 112(5), 1652-1659.