Special considerations regarding CMV in lung transplantation.

Research output: Contribution to journalReview articlepeer-review

Abstract

Lung transplant recipients, more than other organ transplant recipients, are at particular risk for cytomegalovirus (CMV) infection and disease. A major factor in improving management of the lung transplant patient is the ability to prevent or minimize CMV disease, which itself is a major risk factor for opportunistic fungal infections and obliterative bronchiolitis. Strategies being evaluated to improve CMV prophylaxis and consequently graft and patient survival include longer-than-standard courses of prophylactic IV ganciclovir, sequential IV/oral therapy, addition of CMV IG, examining the impact of newer immunosuppressive agents, the role of hypogammaglobulinemia, and potential investigational studies with newer antiviral agents.

Original languageEnglish (US)
Pages (from-to)13-18
Number of pages6
JournalTransplant infectious disease : an official journal of the Transplantation Society
Volume1 Suppl 1
StatePublished - 1999
Externally publishedYes

ASJC Scopus subject areas

  • Transplantation
  • Infectious Diseases

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