Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international experts

Amer M. Zeidan; Prajwal C. Boddu; Mrinal M. Patnaik; Jan Philipp Bewersdorf; Maximilian Stahl; Raajit K. Rampal; Rory Shallis; David P. Steensma; Michael R. Savona; Mikkael A. Sekeres; Gail J. Roboz; Daniel J. DeAngelo; Andre C. Schuh; Eric Padron; Joshua F. Zeidner; Roland B. Walter; Francesco Onida; Amir Fathi; Amy DeZern; Gabriela Hobbs; Eytan M. Stein; Paresh Vyas; Andrew H. Wei; David T. Bowen; Pau Montesinos; Elizabeth A. Griffiths; Amit K. Verma; Alla Keyzner; Michal Bar-Natan; Shyamala C. Navada; Marina Kremyanskaya; Aaron D. Goldberg; Aref Al-Kali; Mark L. Heaney; Aziz Nazha; Huda Salman; Selina Luger; Keith W. Pratz; Heiko Konig; Rami Komrokji; Michael Deininger; Blanca Xicoy Cirici; Vijaya Raj Bhatt; Lewis R. Silverman; Harry P. Erba; Pierre Fenaux; Uwe Platzbecker; Valeria Santini; Eunice S. Wang; Martin S. Tallman; Richard M. Stone; John Mascarenhas

doi:10.1016/S2352-3026(20)30205-2

Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international experts

Amer M. Zeidan, Prajwal C. Boddu, Mrinal M. Patnaik, Jan Philipp Bewersdorf, Maximilian Stahl, Raajit K. Rampal, Rory Shallis, David P. Steensma, Michael R. Savona, Mikkael A. Sekeres, Gail J. Roboz, Daniel J. DeAngelo, Andre C. Schuh, Eric Padron, Joshua F. Zeidner, Roland B. Walter, Francesco Onida, Amir Fathi, Amy DeZern, Gabriela HobbsEytan M. Stein, Paresh Vyas, Andrew H. Wei, David T. Bowen, Pau Montesinos, Elizabeth A. Griffiths, Amit K. Verma, Alla Keyzner, Michal Bar-Natan, Shyamala C. Navada, Marina Kremyanskaya, Aaron D. Goldberg, Aref Al-Kali, Mark L. Heaney, Aziz Nazha, Huda Salman, Selina Luger, Keith W. Pratz, Heiko Konig, Rami Komrokji, Michael Deininger, Blanca Xicoy Cirici, Vijaya Raj Bhatt, Lewis R. Silverman, Harry P. Erba, Pierre Fenaux, Uwe Platzbecker, Valeria Santini, Eunice S. Wang, Martin S. Tallman, Richard M. Stone, John Mascarenhas

School of Medicine

Research output: Contribution to journal › Review article › peer-review

26 Scopus citations

Abstract

The ongoing COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 is a global public health crisis. Multiple observations indicate poorer post-infection outcomes for patients with cancer than for the general population. Herein, we highlight the challenges in caring for patients with acute leukaemias and myeloid neoplasms amid the COVID-19 pandemic. We summarise key changes related to service allocation, clinical and supportive care, clinical trial participation, and ethical considerations regarding the use of lifesaving measures for these patients. We recognise that these recommendations might be more applicable to high-income countries and might not be generalisable because of regional differences in health-care infrastructure, individual circumstances, and a complex and highly fluid health-care environment. Despite these limitations, we aim to provide a general framework for the care of patients with acute leukaemias and myeloid neoplasms during the COVID-19 pandemic on the basis of recommendations from international experts.

Original language	English (US)
Pages (from-to)	e601-e612
Journal	The Lancet Haematology
Volume	7
Issue number	8
DOIs	https://doi.org/10.1016/S2352-3026(20)30205-2
State	Published - Aug 2020

ASJC Scopus subject areas

Hematology

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10.1016/S2352-3026(20)30205-2

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Zeidan, A. M., Boddu, P. C., Patnaik, M. M., Bewersdorf, J. P., Stahl, M., Rampal, R. K., Shallis, R., Steensma, D. P., Savona, M. R., Sekeres, M. A., Roboz, G. J., DeAngelo, D. J., Schuh, A. C., Padron, E., Zeidner, J. F., Walter, R. B., Onida, F., Fathi, A., DeZern, A., ... Mascarenhas, J. (2020). Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international experts. The Lancet Haematology, 7(8), e601-e612. https://doi.org/10.1016/S2352-3026(20)30205-2

Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international experts. / Zeidan, Amer M.; Boddu, Prajwal C.; Patnaik, Mrinal M. et al.
In: The Lancet Haematology, Vol. 7, No. 8, 08.2020, p. e601-e612.

Research output: Contribution to journal › Review article › peer-review

Zeidan, AM, Boddu, PC, Patnaik, MM, Bewersdorf, JP, Stahl, M, Rampal, RK, Shallis, R, Steensma, DP, Savona, MR, Sekeres, MA, Roboz, GJ, DeAngelo, DJ, Schuh, AC, Padron, E, Zeidner, JF, Walter, RB, Onida, F, Fathi, A, DeZern, A, Hobbs, G, Stein, EM, Vyas, P, Wei, AH, Bowen, DT, Montesinos, P, Griffiths, EA, Verma, AK, Keyzner, A, Bar-Natan, M, Navada, SC, Kremyanskaya, M, Goldberg, AD, Al-Kali, A, Heaney, ML, Nazha, A, Salman, H, Luger, S, Pratz, KW, Konig, H, Komrokji, R, Deininger, M, Cirici, BX, Bhatt, VR, Silverman, LR, Erba, HP, Fenaux, P, Platzbecker, U, Santini, V, Wang, ES, Tallman, MS, Stone, RM & Mascarenhas, J 2020, 'Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international experts', The Lancet Haematology, vol. 7, no. 8, pp. e601-e612. https://doi.org/10.1016/S2352-3026(20)30205-2

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title = "Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international experts",

abstract = "The ongoing COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 is a global public health crisis. Multiple observations indicate poorer post-infection outcomes for patients with cancer than for the general population. Herein, we highlight the challenges in caring for patients with acute leukaemias and myeloid neoplasms amid the COVID-19 pandemic. We summarise key changes related to service allocation, clinical and supportive care, clinical trial participation, and ethical considerations regarding the use of lifesaving measures for these patients. We recognise that these recommendations might be more applicable to high-income countries and might not be generalisable because of regional differences in health-care infrastructure, individual circumstances, and a complex and highly fluid health-care environment. Despite these limitations, we aim to provide a general framework for the care of patients with acute leukaemias and myeloid neoplasms during the COVID-19 pandemic on the basis of recommendations from international experts.",

author = "Zeidan, {Amer M.} and Boddu, {Prajwal C.} and Patnaik, {Mrinal M.} and Bewersdorf, {Jan Philipp} and Maximilian Stahl and Rampal, {Raajit K.} and Rory Shallis and Steensma, {David P.} and Savona, {Michael R.} and Sekeres, {Mikkael A.} and Roboz, {Gail J.} and DeAngelo, {Daniel J.} and Schuh, {Andre C.} and Eric Padron and Zeidner, {Joshua F.} and Walter, {Roland B.} and Francesco Onida and Amir Fathi and Amy DeZern and Gabriela Hobbs and Stein, {Eytan M.} and Paresh Vyas and Wei, {Andrew H.} and Bowen, {David T.} and Pau Montesinos and Griffiths, {Elizabeth A.} and Verma, {Amit K.} and Alla Keyzner and Michal Bar-Natan and Navada, {Shyamala C.} and Marina Kremyanskaya and Goldberg, {Aaron D.} and Aref Al-Kali and Heaney, {Mark L.} and Aziz Nazha and Huda Salman and Selina Luger and Pratz, {Keith W.} and Heiko Konig and Rami Komrokji and Michael Deininger and Cirici, {Blanca Xicoy} and Bhatt, {Vijaya Raj} and Silverman, {Lewis R.} and Erba, {Harry P.} and Pierre Fenaux and Uwe Platzbecker and Valeria Santini and Wang, {Eunice S.} and Tallman, {Martin S.} and Stone, {Richard M.} and John Mascarenhas",

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T1 - Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era

T2 - recommendations from a panel of international experts

AU - Zeidan, Amer M.

AU - Boddu, Prajwal C.

AU - Patnaik, Mrinal M.

AU - Bewersdorf, Jan Philipp

AU - Stahl, Maximilian

AU - Rampal, Raajit K.

AU - Shallis, Rory

AU - Steensma, David P.

AU - Savona, Michael R.

AU - Sekeres, Mikkael A.

AU - Roboz, Gail J.

AU - DeAngelo, Daniel J.

AU - Schuh, Andre C.

AU - Padron, Eric

AU - Zeidner, Joshua F.

AU - Walter, Roland B.

AU - Onida, Francesco

AU - Fathi, Amir

AU - DeZern, Amy

AU - Hobbs, Gabriela

AU - Stein, Eytan M.

AU - Vyas, Paresh

AU - Wei, Andrew H.

AU - Bowen, David T.

AU - Montesinos, Pau

AU - Griffiths, Elizabeth A.

AU - Verma, Amit K.

AU - Keyzner, Alla

AU - Bar-Natan, Michal

AU - Navada, Shyamala C.

AU - Kremyanskaya, Marina

AU - Goldberg, Aaron D.

AU - Al-Kali, Aref

AU - Heaney, Mark L.

AU - Nazha, Aziz

AU - Salman, Huda

AU - Luger, Selina

AU - Pratz, Keith W.

AU - Konig, Heiko

AU - Komrokji, Rami

AU - Deininger, Michael

AU - Cirici, Blanca Xicoy

AU - Bhatt, Vijaya Raj

AU - Silverman, Lewis R.

AU - Erba, Harry P.

AU - Fenaux, Pierre

AU - Platzbecker, Uwe

AU - Santini, Valeria

AU - Wang, Eunice S.

AU - Tallman, Martin S.

AU - Stone, Richard M.

AU - Mascarenhas, John

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AB - The ongoing COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 is a global public health crisis. Multiple observations indicate poorer post-infection outcomes for patients with cancer than for the general population. Herein, we highlight the challenges in caring for patients with acute leukaemias and myeloid neoplasms amid the COVID-19 pandemic. We summarise key changes related to service allocation, clinical and supportive care, clinical trial participation, and ethical considerations regarding the use of lifesaving measures for these patients. We recognise that these recommendations might be more applicable to high-income countries and might not be generalisable because of regional differences in health-care infrastructure, individual circumstances, and a complex and highly fluid health-care environment. Despite these limitations, we aim to provide a general framework for the care of patients with acute leukaemias and myeloid neoplasms during the COVID-19 pandemic on the basis of recommendations from international experts.

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Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international experts

Abstract

ASJC Scopus subject areas

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