Spatially resolved imaging of myocardial function with strain-encoded MR: Comparison with delayed contrast-enhanced MR imaging after myocardial infarction

Jérôme Garot, João A.C. Lima, Bernhard L. Gerber, Smita Sampath, Kathy C. Wu, David A. Bluemke, Jerry L. Prince, Nael F. Osman

Research output: Contribution to journalArticlepeer-review

Abstract

Strain-encoded magnetic resonance (MR) imaging was prospectively evaluated for direct imaging of systolic myocardial strain and compared with cross-registered delayed contrast material-enhanced MR imaging in five healthy volunteers and nine patients with infarction. Local contractile performance was decreased in infarcted myocardium versus that in remote and adjacent myocardium (P < .01) and in adjacent versus remote myocardium (P < .05). The extent of dysfunctional myocardium, as assessed with strain-encoded MR imaging, was greater than that of hyperenhancement, as assessed with delayed contrast-enhanced MR imaging (P < .05). Strain values obtained with strain-encoded MR imaging were strongly correlated with those obtained with three-dimensional tagged MR imaging (r = 0.75, P < .001). Strain-encoded MR imaging provides spatially resolved (1.5 x 2.5-mm) imaging and measurement of myocardial strain in humans without the need for postprocessing, which may improve routine comprehensive evaluation of myocardial viability.

Original languageEnglish (US)
Pages (from-to)596-602
Number of pages7
JournalRADIOLOGY
Volume233
Issue number2
DOIs
StatePublished - Nov 2004

Keywords

  • Heart, MR, 511.121412, 511.12143
  • Magnetic resonance (MR), comparative studies
  • Magnetic resonance (MR), contrast enhancement, 511.12143
  • Myocardium, infarction, 511.814

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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