Spatially resolved imaging of myocardial function with strain-encoded MR

Comparison with delayed contrast-enhanced MR imaging after myocardial infarction

Jérôme Garot, Joao Lima, Bernhard L. Gerber, Smita Sampath, Katherine Chih-Ching Wu, David A. Bluemke, Jerry Ladd Prince, Nael Fakhry Osman

Research output: Contribution to journalArticle

Abstract

Strain-encoded magnetic resonance (MR) imaging was prospectively evaluated for direct imaging of systolic myocardial strain and compared with cross-registered delayed contrast material-enhanced MR imaging in five healthy volunteers and nine patients with infarction. Local contractile performance was decreased in infarcted myocardium versus that in remote and adjacent myocardium (P <.01) and in adjacent versus remote myocardium (P <.05). The extent of dysfunctional myocardium, as assessed with strain-encoded MR imaging, was greater than that of hyperenhancement, as assessed with delayed contrast-enhanced MR imaging (P <.05). Strain values obtained with strain-encoded MR imaging were strongly correlated with those obtained with three-dimensional tagged MR imaging (r = 0.75, P <.001). Strain-encoded MR imaging provides spatially resolved (1.5 x 2.5-mm) imaging and measurement of myocardial strain in humans without the need for postprocessing, which may improve routine comprehensive evaluation of myocardial viability.

Original languageEnglish (US)
Pages (from-to)596-602
Number of pages7
JournalRadiology
Volume233
Issue number2
DOIs
StatePublished - Nov 2004

Fingerprint

Magnetic Resonance Spectroscopy
Myocardial Infarction
Magnetic Resonance Imaging
Myocardium
Infarction
Contrast Media
Healthy Volunteers

Keywords

  • Heart, MR, 511.121412, 511.12143
  • Magnetic resonance (MR), comparative studies
  • Magnetic resonance (MR), contrast enhancement, 511.12143
  • Myocardium, infarction, 511.814

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Spatially resolved imaging of myocardial function with strain-encoded MR : Comparison with delayed contrast-enhanced MR imaging after myocardial infarction. / Garot, Jérôme; Lima, Joao; Gerber, Bernhard L.; Sampath, Smita; Wu, Katherine Chih-Ching; Bluemke, David A.; Prince, Jerry Ladd; Osman, Nael Fakhry.

In: Radiology, Vol. 233, No. 2, 11.2004, p. 596-602.

Research output: Contribution to journalArticle

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