Spatial patterns in discordant diagnostic test results for chagas disease: Links to transmission hotspots

Michael Z. Levy, Natalie M. Bowman, Vivian Kawai, Joshua B. Plotkin, Lance A. Waller, Lilia Cabrera, Frank Steurer, Amy E. Seitz, Viviana V. Pinedo-Cancino, Juan Geny Cornejo Del Carpio, Eleazar Cordova Benzaquen, F. Ellis McKenzie, James H. Maguire, Robert H. Gilman, Caryn Bern

Research output: Contribution to journalArticlepeer-review

Abstract

Diagnosis of Chagas disease is hindered by discordance between screening and confirmatory test results for Trypanosoma cruzi infection. In periurban Arequipa, Peru, spatial analysis revealed that individuals with discordant test results are spatially clustered in hotspots of T. cruzi transmission, suggesting that discordant results likely represent true infections in this setting.

Original languageEnglish (US)
Pages (from-to)1104-1106
Number of pages3
JournalClinical Infectious Diseases
Volume48
Issue number8
DOIs
StatePublished - Apr 15 2009

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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