Spatial patterns in discordant diagnostic test results for chagas disease: Links to transmission hotspots

Michael Z. Levy, Natalie M. Bowman, Vivian Kawai, Joshua B. Plotkin, Lance A. Waller, Lilia Cabrera, Frank Steurer, Amy E. Seitz, Viviana V. Pinedo-Cancino, Juan Geny Cornejo Del Carpio, Eleazar Cordova Benzaquen, F. Ellis McKenzie, James H. Maguire, Robert H Gilman, Caryn Bern

Research output: Contribution to journalArticle

Abstract

Diagnosis of Chagas disease is hindered by discordance between screening and confirmatory test results for Trypanosoma cruzi infection. In periurban Arequipa, Peru, spatial analysis revealed that individuals with discordant test results are spatially clustered in hotspots of T. cruzi transmission, suggesting that discordant results likely represent true infections in this setting.

Original languageEnglish (US)
Pages (from-to)1104-1106
Number of pages3
JournalClinical Infectious Diseases
Volume48
Issue number8
DOIs
StatePublished - Apr 15 2009

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Chagas Disease
Trypanosoma cruzi
Routine Diagnostic Tests
Peru
Spatial Analysis
Infection

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)

Cite this

Levy, M. Z., Bowman, N. M., Kawai, V., Plotkin, J. B., Waller, L. A., Cabrera, L., ... Bern, C. (2009). Spatial patterns in discordant diagnostic test results for chagas disease: Links to transmission hotspots. Clinical Infectious Diseases, 48(8), 1104-1106. https://doi.org/10.1086/597464

Spatial patterns in discordant diagnostic test results for chagas disease : Links to transmission hotspots. / Levy, Michael Z.; Bowman, Natalie M.; Kawai, Vivian; Plotkin, Joshua B.; Waller, Lance A.; Cabrera, Lilia; Steurer, Frank; Seitz, Amy E.; Pinedo-Cancino, Viviana V.; Carpio, Juan Geny Cornejo Del; Benzaquen, Eleazar Cordova; McKenzie, F. Ellis; Maguire, James H.; Gilman, Robert H; Bern, Caryn.

In: Clinical Infectious Diseases, Vol. 48, No. 8, 15.04.2009, p. 1104-1106.

Research output: Contribution to journalArticle

Levy, MZ, Bowman, NM, Kawai, V, Plotkin, JB, Waller, LA, Cabrera, L, Steurer, F, Seitz, AE, Pinedo-Cancino, VV, Carpio, JGCD, Benzaquen, EC, McKenzie, FE, Maguire, JH, Gilman, RH & Bern, C 2009, 'Spatial patterns in discordant diagnostic test results for chagas disease: Links to transmission hotspots', Clinical Infectious Diseases, vol. 48, no. 8, pp. 1104-1106. https://doi.org/10.1086/597464
Levy, Michael Z. ; Bowman, Natalie M. ; Kawai, Vivian ; Plotkin, Joshua B. ; Waller, Lance A. ; Cabrera, Lilia ; Steurer, Frank ; Seitz, Amy E. ; Pinedo-Cancino, Viviana V. ; Carpio, Juan Geny Cornejo Del ; Benzaquen, Eleazar Cordova ; McKenzie, F. Ellis ; Maguire, James H. ; Gilman, Robert H ; Bern, Caryn. / Spatial patterns in discordant diagnostic test results for chagas disease : Links to transmission hotspots. In: Clinical Infectious Diseases. 2009 ; Vol. 48, No. 8. pp. 1104-1106.
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