Spatial distribution of syndesmophytes along the vertebral rim in ankylosing spondylitis: Preferential involvement of the posterolateral rim

Sovira Tan, Abhijit Dasgupta, Jianhua Yao, John A. Flynn, Lawrence Yao, Michael M. Ward

Research output: Contribution to journalArticle

Abstract

Objective Syndesmophytes in ankylosing spondylitis (AS) can occur anywhere along the vertebral rim, but little is known about how and where they develop, and particularly if they first form in certain locations along the rim. This information might provide clues to their aetiology. We examined the spatial distribution of syndesmophytes in the thoracolumbar spine in patients with AS using CT. Methods We performed lumbar spine CT scans in 50 patients and used a validated computer algorithm to measure syndesmophyte heights in six intervertebral disc spaces. We measured heights every five radial degrees around the rim of each superior and inferior vertebral endplate. Results Syndesmophytes were observed in 208 of 296 intervertebral disc spaces. Both ascending and descending syndesmophytes were non-randomly distributed along the vertebral rim (p

Original languageEnglish (US)
JournalAnnals of the Rheumatic Diseases
DOIs
StateAccepted/In press - Jan 21 2016

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Computerized tomography
Intervertebral Disc
Ankylosing Spondylitis
Spatial distribution
Spine

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Allergy

Cite this

Spatial distribution of syndesmophytes along the vertebral rim in ankylosing spondylitis : Preferential involvement of the posterolateral rim. / Tan, Sovira; Dasgupta, Abhijit; Yao, Jianhua; Flynn, John A.; Yao, Lawrence; Ward, Michael M.

In: Annals of the Rheumatic Diseases, 21.01.2016.

Research output: Contribution to journalArticle

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