Spatial Bayesian variable selection models on functional magnetic resonance imaging time-series data

Kuo Jung Lee, Galin L. Jones, Brian S. Caffo, Susan S. Bassett

Research output: Contribution to journalArticle

Abstract

A common objective of fMRI (functional magnetic resonance imaging) studies is to determine subject-specific areas of increased blood oxygenation level dependent (BOLD) signal contrast in response to a stimulus or task, and hence to infer regional neuronal activity. We posit and investigate a Bayesian approach that incorporates spatial and temporal dependence and allows for the task-related change in the BOLD signal to change dynamically over the scanning session. In this way, our model accounts for potential learning effects in addition to other mechanisms of temporal drift in task-related signals. We study the properties of the model through its performance on simulated and real data sets.

Original languageEnglish (US)
Pages (from-to)699-732
Number of pages34
JournalBayesian Analysis
Volume9
Issue number3
DOIs
StatePublished - Jan 1 2014

Keywords

  • Bayesian variable selection
  • FmRI
  • Ising distribution
  • Markov chain Monte Carlo

ASJC Scopus subject areas

  • Statistics and Probability
  • Applied Mathematics

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