Spatial Bayesian variable selection models on functional magnetic resonance imaging time-series data

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Abstract

A common objective of fMRI (functional magnetic resonance imaging) studies is to determine subject-specific areas of increased blood oxygenation level dependent (BOLD) signal contrast in response to a stimulus or task, and hence to infer regional neuronal activity. We posit and investigate a Bayesian approach that incorporates spatial and temporal dependence and allows for the task-related change in the BOLD signal to change dynamically over the scanning session. In this way, our model accounts for potential learning effects in addition to other mechanisms of temporal drift in task-related signals. We study the properties of the model through its performance on simulated and real data sets.

Original languageEnglish (US)
Pages (from-to)699-732
Number of pages34
JournalBayesian Analysis
Volume9
Issue number3
DOIs
Publication statusPublished - 2014

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Keywords

  • Bayesian variable selection
  • FmRI
  • Ising distribution
  • Markov chain Monte Carlo

ASJC Scopus subject areas

  • Applied Mathematics
  • Statistics and Probability

Cite this

Spatial Bayesian variable selection models on functional magnetic resonance imaging time-series data. / Lee, Kuo Jung; Jones, Galin L.; Caffo, Brian S; Bassett, Susan.

In: Bayesian Analysis, Vol. 9, No. 3, 2014, p. 699-732.

Research output: Contribution to journalArticle