Southwestern internal medicine conference: Restenosis: The Achilles heel of coronary angioplasty

R. A. Lange, J. E. Willard, L. D. Hillis

Research output: Contribution to journalArticlepeer-review

Abstract

Percutaneous transluminal coronary angioplasty has become the treatment of choice for many patients with symptomatic coronary artery disease. Increased experience with the procedure and improvements in equipment have resulted in high initial success rates; however, a significant number of patients develop restenosis. Insights into the pathophysiologic mechanisms of restenosis have led to the use of various pharmacologic agents and devices to prevent its occurrence. Although many have been successful in decreasing the incidence of restenosis in animal studies, none has yet proven successful in decreasing the incidence of restenosis in humans. Newer approaches and novel therapies are needed to prevent restenosis after percutaneous transluminal coronary angioplasty.

Original languageEnglish (US)
Pages (from-to)265-275
Number of pages11
JournalAmerican Journal of the Medical Sciences
Volume306
Issue number4
StatePublished - 1993
Externally publishedYes

Keywords

  • Coronary angioplasty
  • Restenosis

ASJC Scopus subject areas

  • Medicine(all)

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