Sonographically guided renal mass biopsy: Indications and efficacy

P. T. Johnson, L. N. Nazarian, R. I. Feld, L. Needleman, A. S. Lev-Toaff, S. R. Segal, E. J. Halpern

Research output: Contribution to journalArticle

Abstract

Purpose. To review the clinical indications, pathologic results, and success rate of all our sonographically guided solid renal mass biopsies over a 5-year period. Methods. Between 1993 and 1998, 44 consecutive patients underwent sonographically guided percutaneous biopsy of a solid renal mass. Indications included prior history of nonrenal malignancy, metastatic disease of unknown primary origin, previous contralateral nephrectomy for a renar cell neoplasm, a renal transplant mass, suspected renar lymphoma, history of tuberous sclerosis, and poor surgical candidacy. Aspiration biopsies were initially performed with 22- to 18-gauge spinal needles. If the initial cytologic evaluation findings were nondiagnostic, core biopsies were then performed with 20- to 18-gauge core biopsy guns. Dictated sonographic reports of the biopsies were reviewed to determine the following: indication for biopsy, location and size of the renal mass, needle gauge and type, number of needle passes, and complications. Final cytologic and surgical pathologic records were reviewed. Results. Thirty-six (82%) of the 44 biopsy specimens were diagnostic. Aspirated smears were diagnostic in 24 (67%) of these cases, with the diagnosis made on the basis of cell block alone in an additional 2 (6%). A definitive diagnosis came from core biopsy alone in 10 cases (28%). The 18-gauge core needle yielded diagnostic results more reliably than the 20-gauge core needle, and a significant correlation was seen between core biopsy needle size and the rate of diagnostic core samples (P = .017). Pathologic diagnoses included renal cell carcinoma (n = 18), lymphoma (n = 4), oncocytic neoplasm (n = 4), transitional cell carcinoma (n = 2), angiomyolipoma (n = 1), papillary cortical neoplasm (n = 1), and metastatic carcinoma (n = 6). Complications were seen in 4 (9%) of 44 cases; all were treated conservatively. Conclusions. For specific clinical indications, sonographicarly guided fine-needle aspiration and core biopsy of a solid renal mass can be performed safely. In many cases, a definitive diagnosis can be made on the basis of fine-needle aspiration alone. However, diagnosis may ultimately require core biopsy, for which 18-gauge core needles would be more reriably diagnostic than 20-gauge needles.

Original languageEnglish (US)
Pages (from-to)749-753
Number of pages5
JournalJournal of Ultrasound in Medicine
Volume20
Issue number7
DOIs
StatePublished - 2001

Keywords

  • Biopsy
  • Renal cell carcinoma
  • Renal mass
  • Sonographically guided
  • Ultrasonography

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Sonographically guided renal mass biopsy: Indications and efficacy'. Together they form a unique fingerprint.

  • Cite this

    Johnson, P. T., Nazarian, L. N., Feld, R. I., Needleman, L., Lev-Toaff, A. S., Segal, S. R., & Halpern, E. J. (2001). Sonographically guided renal mass biopsy: Indications and efficacy. Journal of Ultrasound in Medicine, 20(7), 749-753. https://doi.org/10.7863/jum.2001.20.7.749