Sonographically guided fine-needle aspiration biopsy of lytic lesions of the spine: Technique and indications

Sanjay Gupta, Deepak Takhtani, Madhu Gulati, Niranjan Khandelwal, Deepali Gupta, Arvind Rajwanshi, Subhash Gupta, Sudha Suri

Research output: Contribution to journalArticle

Abstract

Purpose. We report the use of sonography to guide fine-needle aspiration biopsies (FNABs) of lytic lesions of the spine. Methods. Twenty-nine patients with lytic vertebral lesions with or without associated extraosseous soft- tissue extension underwent sonographically guided FNAB. Twelve cervical, 7 thoracic, 7 lumbar, and 3 sacral lesions were biopsied. Tissue samples were taken from either the bony lesion through a break in the cortex (n = 9) or the associated soft-tissue extension (n = 20). Results. Adequate diagnostic material obtained in 27 cases (93%) revealed an inflammatory (n = 13) or malignant process (n = 14). Of the 2 patients with inconclusive FNAB findings, 1 patient was lost to follow-up, and the other underwent surgery, which revealed tuberculosis. No complications of FNAB were encountered. Conclusions. We conclude that sonography is a safe and effective guidance modality for FNAB of lytic lesions of the spine, especially for lesions in the cervical region. In the thoracic, lumbar, and sacral regions, however, the role of sonographically guided FNAB is limited to lesions affecting the posterior elements.

Original languageEnglish (US)
Pages (from-to)123-129
Number of pages7
JournalJournal of Clinical Ultrasound
Volume27
Issue number3
DOIs
StatePublished - Mar 1 1999
Externally publishedYes

Fingerprint

Fine Needle Biopsy
Spine
Ultrasonography
Thorax
Sacrococcygeal Region
Lumbosacral Region
Lost to Follow-Up
Tuberculosis

Keywords

  • Bone
  • Spine, biopsy
  • Ultrasonography
  • Ultrasonography, guidance

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Sonographically guided fine-needle aspiration biopsy of lytic lesions of the spine : Technique and indications. / Gupta, Sanjay; Takhtani, Deepak; Gulati, Madhu; Khandelwal, Niranjan; Gupta, Deepali; Rajwanshi, Arvind; Gupta, Subhash; Suri, Sudha.

In: Journal of Clinical Ultrasound, Vol. 27, No. 3, 01.03.1999, p. 123-129.

Research output: Contribution to journalArticle

Gupta, Sanjay ; Takhtani, Deepak ; Gulati, Madhu ; Khandelwal, Niranjan ; Gupta, Deepali ; Rajwanshi, Arvind ; Gupta, Subhash ; Suri, Sudha. / Sonographically guided fine-needle aspiration biopsy of lytic lesions of the spine : Technique and indications. In: Journal of Clinical Ultrasound. 1999 ; Vol. 27, No. 3. pp. 123-129.
@article{d4bc31b6f11648faa3631e04ee0276e6,
title = "Sonographically guided fine-needle aspiration biopsy of lytic lesions of the spine: Technique and indications",
abstract = "Purpose. We report the use of sonography to guide fine-needle aspiration biopsies (FNABs) of lytic lesions of the spine. Methods. Twenty-nine patients with lytic vertebral lesions with or without associated extraosseous soft- tissue extension underwent sonographically guided FNAB. Twelve cervical, 7 thoracic, 7 lumbar, and 3 sacral lesions were biopsied. Tissue samples were taken from either the bony lesion through a break in the cortex (n = 9) or the associated soft-tissue extension (n = 20). Results. Adequate diagnostic material obtained in 27 cases (93{\%}) revealed an inflammatory (n = 13) or malignant process (n = 14). Of the 2 patients with inconclusive FNAB findings, 1 patient was lost to follow-up, and the other underwent surgery, which revealed tuberculosis. No complications of FNAB were encountered. Conclusions. We conclude that sonography is a safe and effective guidance modality for FNAB of lytic lesions of the spine, especially for lesions in the cervical region. In the thoracic, lumbar, and sacral regions, however, the role of sonographically guided FNAB is limited to lesions affecting the posterior elements.",
keywords = "Bone, Spine, biopsy, Ultrasonography, Ultrasonography, guidance",
author = "Sanjay Gupta and Deepak Takhtani and Madhu Gulati and Niranjan Khandelwal and Deepali Gupta and Arvind Rajwanshi and Subhash Gupta and Sudha Suri",
year = "1999",
month = "3",
day = "1",
doi = "10.1002/(SICI)1097-0096(199903/04)27:3<123::AID-JCU4>3.0.CO;2-1",
language = "English (US)",
volume = "27",
pages = "123--129",
journal = "Journal of Clinical Ultrasound",
issn = "0091-2751",
publisher = "John Wiley and Sons Inc.",
number = "3",

}

TY - JOUR

T1 - Sonographically guided fine-needle aspiration biopsy of lytic lesions of the spine

T2 - Technique and indications

AU - Gupta, Sanjay

AU - Takhtani, Deepak

AU - Gulati, Madhu

AU - Khandelwal, Niranjan

AU - Gupta, Deepali

AU - Rajwanshi, Arvind

AU - Gupta, Subhash

AU - Suri, Sudha

PY - 1999/3/1

Y1 - 1999/3/1

N2 - Purpose. We report the use of sonography to guide fine-needle aspiration biopsies (FNABs) of lytic lesions of the spine. Methods. Twenty-nine patients with lytic vertebral lesions with or without associated extraosseous soft- tissue extension underwent sonographically guided FNAB. Twelve cervical, 7 thoracic, 7 lumbar, and 3 sacral lesions were biopsied. Tissue samples were taken from either the bony lesion through a break in the cortex (n = 9) or the associated soft-tissue extension (n = 20). Results. Adequate diagnostic material obtained in 27 cases (93%) revealed an inflammatory (n = 13) or malignant process (n = 14). Of the 2 patients with inconclusive FNAB findings, 1 patient was lost to follow-up, and the other underwent surgery, which revealed tuberculosis. No complications of FNAB were encountered. Conclusions. We conclude that sonography is a safe and effective guidance modality for FNAB of lytic lesions of the spine, especially for lesions in the cervical region. In the thoracic, lumbar, and sacral regions, however, the role of sonographically guided FNAB is limited to lesions affecting the posterior elements.

AB - Purpose. We report the use of sonography to guide fine-needle aspiration biopsies (FNABs) of lytic lesions of the spine. Methods. Twenty-nine patients with lytic vertebral lesions with or without associated extraosseous soft- tissue extension underwent sonographically guided FNAB. Twelve cervical, 7 thoracic, 7 lumbar, and 3 sacral lesions were biopsied. Tissue samples were taken from either the bony lesion through a break in the cortex (n = 9) or the associated soft-tissue extension (n = 20). Results. Adequate diagnostic material obtained in 27 cases (93%) revealed an inflammatory (n = 13) or malignant process (n = 14). Of the 2 patients with inconclusive FNAB findings, 1 patient was lost to follow-up, and the other underwent surgery, which revealed tuberculosis. No complications of FNAB were encountered. Conclusions. We conclude that sonography is a safe and effective guidance modality for FNAB of lytic lesions of the spine, especially for lesions in the cervical region. In the thoracic, lumbar, and sacral regions, however, the role of sonographically guided FNAB is limited to lesions affecting the posterior elements.

KW - Bone

KW - Spine, biopsy

KW - Ultrasonography

KW - Ultrasonography, guidance

UR - http://www.scopus.com/inward/record.url?scp=0032972545&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032972545&partnerID=8YFLogxK

U2 - 10.1002/(SICI)1097-0096(199903/04)27:3<123::AID-JCU4>3.0.CO;2-1

DO - 10.1002/(SICI)1097-0096(199903/04)27:3<123::AID-JCU4>3.0.CO;2-1

M3 - Article

C2 - 10064409

AN - SCOPUS:0032972545

VL - 27

SP - 123

EP - 129

JO - Journal of Clinical Ultrasound

JF - Journal of Clinical Ultrasound

SN - 0091-2751

IS - 3

ER -