Some observations on pyloric gland adenoma: An uncommon and long ignored entity!

Research output: Contribution to journalReview article

Abstract

Pyloric gland adenomas (PGAs) are uncommon to rare and are found mostly in the stomach but in a number of other anatomical sites as well. They were recognised years ago by European and Japanese colleagues whereas North American pathologists learned to diagnose them more recently. They are associated with conditions that result in pyloric metaplasia, the prototype of which is autoimmune gastritis. Since the latter is more common in women and men, gastric PGA has a striking female predominance. There appear to be differences in the distribution of PGA in various populations. Herein we review PGA and note similarities and differences in their distribution in our institutions in Germany and the USA and review their morphological appearance, immunolabelling profile, and preliminary genetic data on these unusual lesions.

Original languageEnglish (US)
Pages (from-to)883-890
Number of pages8
JournalJournal of clinical pathology
Volume67
Issue number10
DOIs
StatePublished - Oct 1 2014

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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