Solitary renal allografts from pediatric cadaver donors less than 2 years of age transplanted into adult recipients

Prodromos G. Borboroglu, Clarence E. Foster, Benjamin Philosophe, Alan C. Farney, John O. Colonna, Eugene J. Schweitzer, Stephen T. Bartlett

Research output: Contribution to journalArticle

Abstract

Background. Transplantation of solitary pediatric renal allografts from donors 2 years of age or younger into adult recipients is controversial. Methods. Between 1998 and 2001, 15 solitary renal allografts from pediatric donors 2 years of age of or younger were transplanted into adult recipients. Thirty-three en bloc renal allografts transplanted between 1994 and 2001 were used for comparison. En bloc kidneys were considered for separation if they measured greater than or equal to 6 cm in length. Renal function (creatinine clearance [CrCl]) was estimated using the Cockroft-Gault formula. Results. Two-year graft survival for the solitary and en bloc groups were 93% and 77%, respectively (P=0.405). Five grafts were lost because of arterial thrombosis (four en bloc and one solitary). Ureteral complications occurred in three grafts in the en bloc group. One-year postoperative CrCl of the surviving solitary (n=14) and en bloc (n=26) grafts were 51.4±26.2 mL/min and 55.1±27.5 ml/min (P>0.05), respectively. Donor weight and kidney length were greater in the solitary group (14.3±3.5 kg and 6.3±0. 4 cm, respectively) compared with the en bloc group (10.8±2.6 kg and 5.9±0.3 cm, respectively) (P=0.001 and P

Original languageEnglish (US)
Pages (from-to)698-702
Number of pages5
JournalTransplantation
Volume77
Issue number5
DOIs
StatePublished - Mar 15 2004
Externally publishedYes

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Cadaver
Allografts
Tissue Donors
Pediatrics
Kidney
Transplants
Creatinine
Graft Survival
Young Adult
Thrombosis
Transplantation
Weights and Measures

ASJC Scopus subject areas

  • Transplantation
  • Immunology

Cite this

Borboroglu, P. G., Foster, C. E., Philosophe, B., Farney, A. C., Colonna, J. O., Schweitzer, E. J., & Bartlett, S. T. (2004). Solitary renal allografts from pediatric cadaver donors less than 2 years of age transplanted into adult recipients. Transplantation, 77(5), 698-702. https://doi.org/10.1097/01.TP.0000114462.10593.9F

Solitary renal allografts from pediatric cadaver donors less than 2 years of age transplanted into adult recipients. / Borboroglu, Prodromos G.; Foster, Clarence E.; Philosophe, Benjamin; Farney, Alan C.; Colonna, John O.; Schweitzer, Eugene J.; Bartlett, Stephen T.

In: Transplantation, Vol. 77, No. 5, 15.03.2004, p. 698-702.

Research output: Contribution to journalArticle

Borboroglu, Prodromos G. ; Foster, Clarence E. ; Philosophe, Benjamin ; Farney, Alan C. ; Colonna, John O. ; Schweitzer, Eugene J. ; Bartlett, Stephen T. / Solitary renal allografts from pediatric cadaver donors less than 2 years of age transplanted into adult recipients. In: Transplantation. 2004 ; Vol. 77, No. 5. pp. 698-702.
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