TY - JOUR
T1 - Solitary epithelioid histiocytoma (reticulohistiocytoma) of the glans penis
AU - Mannan, A. A.A.S.Rifat
AU - Kahvic, Mirza
AU - Singh, Naorem Gopendro
AU - Zahir, Mohammed
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2012/10
Y1 - 2012/10
N2 - Solitary epithelioid histiocytoma (previously called reticulohistiocytoma) is a rare benign dermal histiocytic proliferation characterized by the presence of large, eosinophilic histiocytes with 'glassy' cytoplasm. This entity assumes importance because of its close histologic resemblance to several benign as well as malignant cutaneous lesions. Involvement of the penis is extremely rare, and to our knowledge, only one case has been previously described in the literature.We report a case of solitary epithelioid histiocytoma in a 34-year-old man who presented with a nodule in the glans penis. Microscopy showed proliferation of large epithelioid histiocytes with abundant eosinophilic cytoplasm, which expressed CD68, CD163 and vimentin. This case highlights the significance of recognizing this unusual lesion and differentiating it from its histologic mimics.
AB - Solitary epithelioid histiocytoma (previously called reticulohistiocytoma) is a rare benign dermal histiocytic proliferation characterized by the presence of large, eosinophilic histiocytes with 'glassy' cytoplasm. This entity assumes importance because of its close histologic resemblance to several benign as well as malignant cutaneous lesions. Involvement of the penis is extremely rare, and to our knowledge, only one case has been previously described in the literature.We report a case of solitary epithelioid histiocytoma in a 34-year-old man who presented with a nodule in the glans penis. Microscopy showed proliferation of large epithelioid histiocytes with abundant eosinophilic cytoplasm, which expressed CD68, CD163 and vimentin. This case highlights the significance of recognizing this unusual lesion and differentiating it from its histologic mimics.
KW - Histiocyte
KW - Penis
KW - Reticulohistiocytoma
KW - Skin
KW - Solitary epithelioid histiocytoma
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U2 - 10.1007/s11255-012-0248-3
DO - 10.1007/s11255-012-0248-3
M3 - Article
C2 - 22777481
AN - SCOPUS:84867860257
SN - 0301-1623
VL - 44
SP - 1345
EP - 1348
JO - International urology and nephrology
JF - International urology and nephrology
IS - 5
ER -