Soft tissue sarcoma, version 2.2016: Clinical practice guidelines in oncology

Margaret Von Mehren, R. Lor Randall, Robert S. Benjamin, Sarah Boles, Marilyn M. Bui, Ernest U. Conrad, Kristen N. Ganjoo, Suzanne George, Ricardo J. Gonzalez, Martin J. Heslin, John M. Kane, Henry Koon, Joel Mayerson, Martin McCarter, Sean V. McGarry, Christian Meyer, Richard J. O'Donnell, Alberto S. Pappo, I. Benjamin Paz, Ivy A. PetersenJohn D. Pfeifer, Richard F. Riedel, Scott Schuetze, Karen D. Schupak, Herbert S. Schwartz, William D. Tap, Jeffrey D. Wayne, Mary Anne Bergman, Jillian Scavone

Research output: Contribution to journalArticle

Abstract

Soft tissue sarcomas (STS) are rare solid tumors of mesenchymal cell origin that display a heterogenous mix of clinical and pathologic characteristics. STS can develop from fat, muscle, nerves, blood vessels, and other connective tissues. The evaluation and treatment of patients with STS requires a multidisciplinary team with demonstrated expertise in the management of these tumors. The complete NCCN Guidelines for Soft Tissue Sarcoma (available at NCCN.org) provide recommendations for the diagnosis, evaluation, and treatment of extremity/superficial trunk/head and neck STS, as well as intra-abdominal/retroperitoneal STS, gastrointestinal stromal tumor, desmoid tumors, and rhabdomyosarcoma. This manuscript discusses guiding principles for the diagnosis and staging of STS and evidence for treatment modalities that include surgery, radiation, chemoradiation, chemotherapy, and targeted therapy.

Original languageEnglish (US)
Pages (from-to)758-786
Number of pages29
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume14
Issue number6
DOIs
Publication statusPublished - Jun 1 2016

    Fingerprint

ASJC Scopus subject areas

  • Oncology

Cite this

Von Mehren, M., Randall, R. L., Benjamin, R. S., Boles, S., Bui, M. M., Conrad, E. U., ... Scavone, J. (2016). Soft tissue sarcoma, version 2.2016: Clinical practice guidelines in oncology. JNCCN Journal of the National Comprehensive Cancer Network, 14(6), 758-786. https://doi.org/10.6004/jnccn.2016.0078