Smoking cessation interventions in COPD: A networkmeta-analysis of randomised trials

R. Strassmann, B. Bausch, A. Spaar, J. Kleijnen, O. Braendli, M. A. Puhan

Research output: Contribution to journalArticle

Abstract

The aim of this study was to rank order the effectiveness of smoking cessation interventions for chronic obstructive pulmonary disease (COPD) patients. We searched 10 databases to identify randomised trials of smoking cessation counselling (SCC) with or without pharmacotherapy or nicotine replacement therapy (NRT). We conducted a network meta-analysis using logistic regression analyses to assess the comparative effectiveness of smoking cessation interventions while preserving randomisation of each trial. The analysis of 7,372 COPD patients from six out of eight identified trials showed that SCC in combination with NRT had the greatest effect on prolonged abstinence rates versus usual care (OR 5.08, p

Original languageEnglish (US)
Pages (from-to)634-640
Number of pages7
JournalEuropean Respiratory Journal
Volume34
Issue number3
DOIs
StatePublished - Sep 2009

Keywords

  • Chronic obstructive pulmonary disease
  • Mortality
  • Network meta-analysis
  • Prolonged abstinence rates
  • Randomised trials
  • Smoking cessation

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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    Strassmann, R., Bausch, B., Spaar, A., Kleijnen, J., Braendli, O., & Puhan, M. A. (2009). Smoking cessation interventions in COPD: A networkmeta-analysis of randomised trials. European Respiratory Journal, 34(3), 634-640. https://doi.org/10.1183/09031936.00167708