Smoking cessation interventions in COPD: A networkmeta-analysis of randomised trials

R. Strassmann; B. Bausch; A. Spaar; J. Kleijnen; O. Braendli; M. A. Puhan

doi:10.1183/09031936.00167708

Smoking cessation interventions in COPD: A networkmeta-analysis of randomised trials

R. Strassmann, B. Bausch, A. Spaar, J. Kleijnen, O. Braendli, M. A. Puhan

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

85 Scopus citations

Abstract

The aim of this study was to rank order the effectiveness of smoking cessation interventions for chronic obstructive pulmonary disease (COPD) patients. We searched 10 databases to identify randomised trials of smoking cessation counselling (SCC) with or without pharmacotherapy or nicotine replacement therapy (NRT). We conducted a network meta-analysis using logistic regression analyses to assess the comparative effectiveness of smoking cessation interventions while preserving randomisation of each trial. The analysis of 7,372 COPD patients from six out of eight identified trials showed that SCC in combination with NRT had the greatest effect on prolonged abstinence rates versus usual care (OR 5.08, p

Original language	English (US)
Pages (from-to)	634-640
Number of pages	7
Journal	European Respiratory Journal
Volume	34
Issue number	3
DOIs	https://doi.org/10.1183/09031936.00167708
State	Published - Sep 2009

Keywords

Chronic obstructive pulmonary disease
Mortality
Network meta-analysis
Prolonged abstinence rates
Randomised trials
Smoking cessation

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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10.1183/09031936.00167708

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Smoking cessation interventions in COPD: A networkmeta-analysis of randomised trials

Abstract

Keywords

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