Smoking and age-related macular degeneration: Review and update

Sara Velilla, José Javier García-Medina, Alfredo García-Layana, Rosa Dolz-Marco, Sheila Pons-Vázquez, M. Dolores Pinazo-Durán, Francisco Gómez-Ulla, J. Fernando Arévalo, Manuel Díaz-Llopis, Roberto Gallego-Pinazo

Research output: Contribution to journalReview article


Age-related macular degeneration (AMD) is one of the main socioeconomical health issues worldwide. AMD has a multifactorial etiology with a variety of risk factors. Smoking is the most important modifiable risk factor for AMD development and progression. The present review summarizes the epidemiological studies evaluating the association between smoking and AMD, the mechanisms through which smoking induces damage to the chorioretinal tissues, and the relevance of advising patients to quit smoking for their visual health.

Original languageEnglish (US)
Article number895147
JournalJournal of Ophthalmology
StatePublished - Dec 1 2013


ASJC Scopus subject areas

  • Ophthalmology

Cite this

Velilla, S., García-Medina, J. J., García-Layana, A., Dolz-Marco, R., Pons-Vázquez, S., Pinazo-Durán, M. D., Gómez-Ulla, F., Arévalo, J. F., Díaz-Llopis, M., & Gallego-Pinazo, R. (2013). Smoking and age-related macular degeneration: Review and update. Journal of Ophthalmology, 2013, [895147].