Small serotonin-producing neuroendocrine tumor of the pancreas associated with pancreatic duct obstruction

Satomi Kawamoto, Chanjuan Shi, Ralph H. Hruban, Michael A. Choti, Richard D. Schulick, Elliot K. Fishman, Stanley S. Siegelman

Research output: Contribution to journalReview article

Abstract

OBJECTIVE. Pancreatic neuroendocrine tumors expressing serotonin (carcinoid tumors) account for a small portion of pancreatic neuroendocrine tumors. The purpose of this study was to describe cases of small serotonin-producing pancreatic neuroendocrine tumors associated with pancreatic duct obstruction. CONCLUSION. Serotonin produced by pancreatic neuroendocrine tumors can induce fibrosis and pancreatic duct obstruction. Pancreatic neuroendocrine tumors should be considered when CT shows a small hypervascular mass associated with upstream pancreatic duct dilatation or atrophy. Evidence of small pancreatic neuroendocrine tumors should be sought in cases of idiopathic pancreatic duct stenosis.

Original languageEnglish (US)
Pages (from-to)W482-W488
JournalAmerican Journal of Roentgenology
Volume197
Issue number3
DOIs
StatePublished - Sep 1 2011

Keywords

  • Pancreatic atrophy
  • Pancreatic duct obstruction
  • Pancreatic neuroendocrine tumor
  • Serotonin

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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