Small intestinal infections: Salmonella and human immunodeficiency virus-associated enteropathy

L. M. Mundy, C. L. Sears

Research output: Contribution to journalReview article

Abstract

Salmonella gastroenteritis is an important, common, and usually self-limited illness. Problems relating to invasive salmonellosis in immunocompromised hosts, chronic carriage, and increasing antibiotic resistance have made the management of salmonella infections more complex. This article reviews salmonellosis, focusing on recent epidemiology, pathophysiology, and treatment considerations. Areas of recent investigation of mechanisms of pathogenesis, including signal transduction pathways, the role of cytokines, and the mechanisms of the heat-labile enterotoxin, are reviewed. New concepts are also considered for enteropathy associated with human immunodeficiency virus.

Original languageEnglish (US)
Pages (from-to)77-82
Number of pages6
JournalCurrent opinion in gastroenterology
Volume9
Issue number1
DOIs
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • Gastroenterology

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