Abstract
Primary small cell carcinoma of the larynx is a rare malignancy with a dismal prognosis. A survey of the long-term follow-up from reported cases of small cell carcinoma of the larynx and a review of the recent experience with this tumor at the University of Michigan Hospitals was undertaken to determine if newer treatment approaches incorporating adjuvant chemotherapy were associated with prolonged survival. Median survival for these patients receiving adjuvant chemotherapy was 19 months compared to 11 months for patients treated with surgery and/or radiation therapy alone. Among patients treated initially with primary radiation therapy and adjuvant chemotherapy median survival was 55 months, which was significantly longer than any other treatment regimen (P=0.02). Systemic chemotherapy and therapeutic irradiation appears to offer the least disabling and most efficacious form of current therapy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1283-1290 |
| Number of pages | 8 |
| Journal | Laryngoscope |
| Volume | 96 |
| Issue number | 11 |
| State | Published - 1986 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Otorhinolaryngology
Cite this
Small cell carcinoma of the larynx : Results of therapy. / Baugh, R. F.; Wolf, G. T.; Beals, T. F.; Krause, C. J.; Forastiere, Arlene A.
In: Laryngoscope, Vol. 96, No. 11, 1986, p. 1283-1290.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Small cell carcinoma of the larynx
T2 - Results of therapy
AU - Baugh, R. F.
AU - Wolf, G. T.
AU - Beals, T. F.
AU - Krause, C. J.
AU - Forastiere, Arlene A.
PY - 1986
Y1 - 1986
N2 - Primary small cell carcinoma of the larynx is a rare malignancy with a dismal prognosis. A survey of the long-term follow-up from reported cases of small cell carcinoma of the larynx and a review of the recent experience with this tumor at the University of Michigan Hospitals was undertaken to determine if newer treatment approaches incorporating adjuvant chemotherapy were associated with prolonged survival. Median survival for these patients receiving adjuvant chemotherapy was 19 months compared to 11 months for patients treated with surgery and/or radiation therapy alone. Among patients treated initially with primary radiation therapy and adjuvant chemotherapy median survival was 55 months, which was significantly longer than any other treatment regimen (P=0.02). Systemic chemotherapy and therapeutic irradiation appears to offer the least disabling and most efficacious form of current therapy.
AB - Primary small cell carcinoma of the larynx is a rare malignancy with a dismal prognosis. A survey of the long-term follow-up from reported cases of small cell carcinoma of the larynx and a review of the recent experience with this tumor at the University of Michigan Hospitals was undertaken to determine if newer treatment approaches incorporating adjuvant chemotherapy were associated with prolonged survival. Median survival for these patients receiving adjuvant chemotherapy was 19 months compared to 11 months for patients treated with surgery and/or radiation therapy alone. Among patients treated initially with primary radiation therapy and adjuvant chemotherapy median survival was 55 months, which was significantly longer than any other treatment regimen (P=0.02). Systemic chemotherapy and therapeutic irradiation appears to offer the least disabling and most efficacious form of current therapy.
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M3 - Article
C2 - 3022085
AN - SCOPUS:0022967410
VL - 96
SP - 1283
EP - 1290
JO - Laryngoscope
JF - Laryngoscope
SN - 0023-852X
IS - 11
ER -