TY - GEN
T1 - Small animal radiation research platform
T2 - 10th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2007
AU - Matinfar, Mohammad
AU - Gray, Owen
AU - Iordachita, Iulian
AU - Kennedy, Chris
AU - Ford, Eric
AU - Wong, John
AU - Taylor, Russell H.
AU - Kazanzides, Peter
PY - 2007
Y1 - 2007
N2 - In cancer research, well characterized small animal models of human cancer, such as transgenic mice, have greatly accelerated the pace of development of cancer treatments. The goal of the Small Animal Radiation Research Platform (SARRP) is to make those same models available for the development and evaluation of novel radiation therapies. In combination with advanced imaging methods, small animal research allows detailed study of biological processes, disease progression, and response to therapy, with the potential to provide a natural bridge to the clinical environment. The SARRP will realistically model human radiation treatment methods in standard animal models. In this paper, we describe the mechanical and control structure of the system. This system requires accurate calibration of the x-ray beam for both imaging and radiation treatment, which is presented in detail in the paper.
AB - In cancer research, well characterized small animal models of human cancer, such as transgenic mice, have greatly accelerated the pace of development of cancer treatments. The goal of the Small Animal Radiation Research Platform (SARRP) is to make those same models available for the development and evaluation of novel radiation therapies. In combination with advanced imaging methods, small animal research allows detailed study of biological processes, disease progression, and response to therapy, with the potential to provide a natural bridge to the clinical environment. The SARRP will realistically model human radiation treatment methods in standard animal models. In this paper, we describe the mechanical and control structure of the system. This system requires accurate calibration of the x-ray beam for both imaging and radiation treatment, which is presented in detail in the paper.
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U2 - 10.1007/978-3-540-75759-7_112
DO - 10.1007/978-3-540-75759-7_112
M3 - Conference contribution
C2 - 18044657
AN - SCOPUS:79551682210
SN - 9783540757580
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 926
EP - 934
BT - Medical Image Computing and Computer-Assisted Intervention - MICCAI 2007 - 10th International Conference, Proceedings
PB - Springer Verlag
Y2 - 29 October 2007 through 2 November 2007
ER -