Small animal radiation research platform: Imaging, mechanics, control and calibration

Mohammad Matinfar, Owen Gray, Iulian Iordachita, Chris Kennedy, Eric Ford, John Wong, Russell H. Taylor, Peter Kazanzides

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In cancer research, well characterized small animal models of human cancer, such as transgenic mice, have greatly accelerated the pace of development of cancer treatments. The goal of the Small Animal Radiation Research Platform (SARRP) is to make those same models available for the development and evaluation of novel radiation therapies. In combination with advanced imaging methods, small animal research allows detailed study of biological processes, disease progression, and response to therapy, with the potential to provide a natural bridge to the clinical environment. The SARRP will realistically model human radiation treatment methods in standard animal models. In this paper, we describe the mechanical and control structure of the system. This system requires accurate calibration of the x-ray beam for both imaging and radiation treatment, which is presented in detail in the paper.

Original languageEnglish (US)
Title of host publicationMedical Image Computing and Computer-Assisted Intervention - MICCAI 2007 - 10th International Conference, Proceedings
PublisherSpringer Verlag
Pages926-934
Number of pages9
EditionPART 2
ISBN (Print)9783540757580
DOIs
StatePublished - 2007
Event10th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2007 - Brisbane, Australia
Duration: Oct 29 2007Nov 2 2007

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 2
Volume4792 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other10th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2007
CountryAustralia
CityBrisbane
Period10/29/0711/2/07

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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