Sleep disorders in the elderly with and without chronic airflow obstruction: The SARA study

Vincenzo Bellia, Filippo Catalano, Nicola Scichilone, Raffaele Antonelli Incalzi, Mario Spatafora, Carlo Vergani, Franco Rengo

Research output: Contribution to journalArticlepeer-review

81 Scopus citations


Objectives: Our objectives were to test the hypothesis that, in the geriatric population, chronic airway obstruction is associated with a higher prevalence of sleep disturbances; to identify the main correlates of sleep disturbances, and to verify whether asthma and COPD patients have different patterns of sleep disturbances. Methods: The EPESE questionnaire was administered to 734 patients aged 65 years and over with asthma or chronic obstructive pulmonary disease (cases) and 1237 individuals of comparable age who were free of respiratory disease but not of other chronic conditions (controls). Four sleep disturbances were quantified: difficulty in falling asleep, nocturnal awakening, morning tiredness, and early awakening. Multidimensional assessment of demographic data, personal history, clinical, and functional status was performed. Independent correlates of sleep disturbances were identified by logistic regression analysis. Results: One or more sleep disturbances were reported by 445 cases and 697 controls (60.6% vs. 56.4%, ns). Morning tiredness and early awakenings were more prevalent among cases (38% vs. 27.8%, p<0.001, and 35.1% vs. 28%, p<0.001, respectively). Depression, as assessed by the 15-item Geriatric Depression Scale, was the most significant independent correlate for all sleep scores. Both being a case and having arthritis were independent correlates of three out of the four sleep disturbances. Conclusions: Selected sleep disturbances are more common among elderly patients with chronic airway diseases than in those with chronic non-respiratory diseases. Depressed mood and coexisting arthritis are the most relevant independent correlates of sleep disturbances.

Original languageEnglish (US)
Pages (from-to)318-323
Number of pages6
Issue number3
StatePublished - May 1 2003
Externally publishedYes


  • COPD and asthma
  • Elderly
  • Sleep disturbances

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology (medical)


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