TY - JOUR
T1 - Sleep-disordered breathing and caffeine consumption
T2 - Results of a community-based study
AU - Aurora, R. Nisha
AU - Crainiceanu, Ciprian
AU - Caffo, Brian
AU - Punjabi, Naresh M.
N1 - Funding Information:
Financial/nonfinancial disclosures: The authors have reported to CHEST the following conflicts of interest: Dr Crainiceanu has a consulting contract with Merck & Co, Inc, for statistical methods support for the analysis of EEG spectrogram data. The data analyzed and the scientific problems are unrelated to the topic of the current manuscript. Dr Crainiceanu is also consulting with On-X Life Technologies, Inc, on statistical methods for the design and analysis of adaptive clinical trials with application to mitral valve implant clinical trials. The data and scientific problems are unrelated to the current manuscript. Dr Caffo has provided consulting services to entities delivering products in this area. The consulting had no scientific overlap with the current work. Dr Punjabi has received research grant support from ResMed. Dr Aurora has reported that no potential conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.
PY - 2012/9
Y1 - 2012/9
N2 - Background: Sleepiness is one of the most burdensome symptoms of sleep-disordered breathing (SDB). While caffeine is frequently used to avert sleepiness, the association between SDB and caffeine use has not been thoroughly explored. The current study examined whether SDB is associated with caffeine consumption and if factors such as sex, age, and daytime sleepiness explain or modify the association. Methods: Data from the Sleep Heart Health Study, a community-based study on the consequences of SDB, were used to characterize the association between SDB and caffeine intake. SDB was assessed with full-montage polysomnography. Caffeine use was quantified as the number of cans of soda or the cups of coffee or tea consumed daily. The Epworth Sleepiness Scale was used to assess daytime sleepiness. Multivariable negative binomial regression models were used to characterize the independent association between SDB and caffeine use. Results: Caffeinated soda, but not tea or coffee, intake was independently associated with SDB severity. Compared with participants without SDB, the relative ratios for caffeinated soda consumption in women with mild, moderate, and severe SDB were 1.20(CI, 1.03-1.41), 1.46(CI, 1.14-1.87), and 1.73(CI, 1.23-2.42), respectively. For men, an association was only noted with severe SDB and caffeinated soda use. Age did not modify the SDB-caffeine association, and sleepiness could not explain the observed associations. Conclusions: SDB is independently associated with caffeinated soda use in the general community. Identifying excessive caffeine used in SDB has potential significance given the cardiovascular effects of caffeine and untreated SDB.
AB - Background: Sleepiness is one of the most burdensome symptoms of sleep-disordered breathing (SDB). While caffeine is frequently used to avert sleepiness, the association between SDB and caffeine use has not been thoroughly explored. The current study examined whether SDB is associated with caffeine consumption and if factors such as sex, age, and daytime sleepiness explain or modify the association. Methods: Data from the Sleep Heart Health Study, a community-based study on the consequences of SDB, were used to characterize the association between SDB and caffeine intake. SDB was assessed with full-montage polysomnography. Caffeine use was quantified as the number of cans of soda or the cups of coffee or tea consumed daily. The Epworth Sleepiness Scale was used to assess daytime sleepiness. Multivariable negative binomial regression models were used to characterize the independent association between SDB and caffeine use. Results: Caffeinated soda, but not tea or coffee, intake was independently associated with SDB severity. Compared with participants without SDB, the relative ratios for caffeinated soda consumption in women with mild, moderate, and severe SDB were 1.20(CI, 1.03-1.41), 1.46(CI, 1.14-1.87), and 1.73(CI, 1.23-2.42), respectively. For men, an association was only noted with severe SDB and caffeinated soda use. Age did not modify the SDB-caffeine association, and sleepiness could not explain the observed associations. Conclusions: SDB is independently associated with caffeinated soda use in the general community. Identifying excessive caffeine used in SDB has potential significance given the cardiovascular effects of caffeine and untreated SDB.
UR - http://www.scopus.com/inward/record.url?scp=84865849247&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84865849247&partnerID=8YFLogxK
U2 - 10.1378/chest.11-2894
DO - 10.1378/chest.11-2894
M3 - Article
C2 - 22459776
AN - SCOPUS:84865849247
SN - 0012-3692
VL - 142
SP - 631
EP - 638
JO - CHEST
JF - CHEST
IS - 3
ER -