To the Editor: With regard to the findings of elevated histaminase activity in medullary carcinoma of the thyroid gland by Baylin et al. in the Journal (283:1239–1233, 1970), we should like to pass on the information that a few months ago, Dr. Jules L. Baum, of the New England Medical Center Hospitals, approached me about performing an intradermal histamine (1:1,000) test on one of our patients with multiple mucosal neuromas, medullary carcinoma of the thyroid gland and pheochromocytoma. He observed an absence of axon flare after injection. This test was performed because his patient who had the same syndrome exhibited ….
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