Skin metastasis from conventional giant cell tumor of bone: Conceptual significance

W. Tyler, T. Barrett, F. Frassica, E. McCarthy

Research output: Contribution to journalArticle


A conventional giant cell tumor of the proximal femur recurred twice locally and developed pulmonary nodules. The lung lesions were felt to be an example of "benign" metastases. Eight months after the initial presentation, the patient developed a single skin nodule on the contralateral leg. Histologic features of the skin nodule showed conventional giant cell tumor identical to the bone lesion. This nodule is a manifestation of arterial metastasis typical of any malignant tumor and seemingly contradicts the concept of "benign" metastasis.

Original languageEnglish (US)
Pages (from-to)166-170
Number of pages5
JournalSkeletal Radiology
Issue number3
StatePublished - Dec 1 2002



  • Arterial metastasis
  • Femur-conventional giant cell tumor
  • Radiographs
  • Skin metastasis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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