Abstract
Flecainide acetate is a classic Ic antiarrhythmic agent used to treat a variety of cardiac arrhythmias. Non-cardiac side effects usually affect the central nervous system. Few case reports of possible flecainide-induced peripheral neuropathy have been reported. We report this unique case in that flecainide-induced sensory neuropathy was confirmed with skin biopsy, and subsequent improvement of neuropathy was documented with assessment of intraepidermal nerve fiber density in a repeat nerve biopsy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 144-146 |
| Number of pages | 3 |
| Journal | Muscle and Nerve |
| Volume | 45 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2012 |
Keywords
- Flecainide
- Peripheral neuropathy
- Potassium channel
- Skin biopsy
- Toxic neuropathy
ASJC Scopus subject areas
- Physiology
- Clinical Neurology
- Cellular and Molecular Neuroscience
- Physiology (medical)
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Cite this
Burakgazi, A. Z., Polydefkis, M., & Höke, A. (2012). Skin biopsy-proven flecainide-induced neuropathy. Muscle and Nerve, 45(1), 144-146. https://doi.org/10.1002/mus.22239