Skill learning and repetition priming in Alzheimer's disease

E. Grober, R. Ausubel, M. Sliwinski, B. Gordon

Research output: Contribution to journalArticlepeer-review

Abstract

While perceptual-motor learning occurs normally in Alzheimer's disease (AD) patients, their ability to acquire the skill of reading transformed text has not been well delineated. AD patients and matched controls were timed as they read two blocks of words presented in mirror image. Control subjects displayed both skill learning and repetition priming, whereas AD patients displayed only repetition priming. Skill learning in AD patients was associated with their ability to complete verbal analogies. They displayed the expected impairment in recognition for the words from the mirror reading task. The failure of AD patients to acquire the mirror reading skill can be understood through a task analysis and may reflect an underlying deficit in abstract reasoning that precludes the development of appropriate pattern analyzing strategies needed to transform rotated text.

Original languageEnglish (US)
Pages (from-to)849-858
Number of pages10
JournalNeuropsychologia
Volume30
Issue number10
DOIs
StatePublished - Oct 1992

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience
  • Behavioral Neuroscience

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