Abstract
Background: Six-minute walk distance (6MWD) and maximal oxygen uptake (VO2max) are used as prognostic tools in patients with heart failure (HF). Whether these tests provide similar information in the LVAD population is not known. Methods: Eight patients supported with VentrAssist rotary blood pump LVADs, underwent three days of testing that included 6MWD and VO2 max at normal, high or low speeds, generating twenty-four paired results. Results: The mean 6MWD was 438 (+/- 90 SD) m and the mean VO2 (max) was 14.12 (+/-1.87) ml/kg/ min. There was a modest correlation between VO2 (max) and 6MWD (r = 0.56 p = 0.004), which improved (r = 0.72 p = 0.002) when patients with higher resting Pro BNP levels and larger left ventricular end diastolic diameters (LVEDD) were excluded. Conclusions: 6MWD is correlated with VO2 (max) in LVAD supported patients, with higher correlations in patients with better underlying cardiac function.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 539-545 |
| Number of pages | 7 |
| Journal | International Journal of Artificial Organs |
| Volume | 37 |
| Issue number | 7 |
| DOIs | |
| State | Published - 2014 |
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Keywords
- Cardiomyopathies
- Cardiopulmonary exercise test
- Exercise test
- Heart-assist devices
- Six minute walk test
- Ventricular-assist devices
ASJC Scopus subject areas
- Biomaterials
- Biomedical Engineering
- Bioengineering
- Medicine (miscellaneous)
- Medicine(all)
Cite this
Six-minute walk distance predicts VO2 (max) in patients supported with continuous flow left ventricular assist devices. / Prichard, Roslyn A.; Juul, Marcus; Gazibarich, Gary; Davidson, Patricia M; Mason, Carmel; Keogh, Anne M.; Macdonald, Peter S.; Hayward, Christopher S.
In: International Journal of Artificial Organs, Vol. 37, No. 7, 2014, p. 539-545.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Six-minute walk distance predicts VO2 (max) in patients supported with continuous flow left ventricular assist devices
AU - Prichard, Roslyn A.
AU - Juul, Marcus
AU - Gazibarich, Gary
AU - Davidson, Patricia M
AU - Mason, Carmel
AU - Keogh, Anne M.
AU - Macdonald, Peter S.
AU - Hayward, Christopher S.
PY - 2014
Y1 - 2014
N2 - Background: Six-minute walk distance (6MWD) and maximal oxygen uptake (VO2max) are used as prognostic tools in patients with heart failure (HF). Whether these tests provide similar information in the LVAD population is not known. Methods: Eight patients supported with VentrAssist rotary blood pump LVADs, underwent three days of testing that included 6MWD and VO2 max at normal, high or low speeds, generating twenty-four paired results. Results: The mean 6MWD was 438 (+/- 90 SD) m and the mean VO2 (max) was 14.12 (+/-1.87) ml/kg/ min. There was a modest correlation between VO2 (max) and 6MWD (r = 0.56 p = 0.004), which improved (r = 0.72 p = 0.002) when patients with higher resting Pro BNP levels and larger left ventricular end diastolic diameters (LVEDD) were excluded. Conclusions: 6MWD is correlated with VO2 (max) in LVAD supported patients, with higher correlations in patients with better underlying cardiac function.
AB - Background: Six-minute walk distance (6MWD) and maximal oxygen uptake (VO2max) are used as prognostic tools in patients with heart failure (HF). Whether these tests provide similar information in the LVAD population is not known. Methods: Eight patients supported with VentrAssist rotary blood pump LVADs, underwent three days of testing that included 6MWD and VO2 max at normal, high or low speeds, generating twenty-four paired results. Results: The mean 6MWD was 438 (+/- 90 SD) m and the mean VO2 (max) was 14.12 (+/-1.87) ml/kg/ min. There was a modest correlation between VO2 (max) and 6MWD (r = 0.56 p = 0.004), which improved (r = 0.72 p = 0.002) when patients with higher resting Pro BNP levels and larger left ventricular end diastolic diameters (LVEDD) were excluded. Conclusions: 6MWD is correlated with VO2 (max) in LVAD supported patients, with higher correlations in patients with better underlying cardiac function.
KW - Cardiomyopathies
KW - Cardiopulmonary exercise test
KW - Exercise test
KW - Heart-assist devices
KW - Six minute walk test
KW - Ventricular-assist devices
UR - http://www.scopus.com/inward/record.url?scp=84905217935&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84905217935&partnerID=8YFLogxK
U2 - 10.5301/ijao.5000345
DO - 10.5301/ijao.5000345
M3 - Article
C2 - 25044385
AN - SCOPUS:84905217935
VL - 37
SP - 539
EP - 545
JO - International Journal of Artificial Organs
JF - International Journal of Artificial Organs
SN - 0391-3988
IS - 7
ER -