Single T cell probes for antigen/MHC expression

Research output: Contribution to journalArticlepeer-review


T-cell receptor binding to the antigen/MHC ligand on the surface of antigen-presenting cells is the central event in T-cell activation. Methods have been developed for measuring this recognition event in single T cells and have allowed their use as 'probes' for antigen/MHC expression. Single cell assays have allowed analysis of early events in T-cell activation, and of unknown ligands recognized by the T-cell receptor.

Original languageEnglish (US)
Pages (from-to)258-262
Number of pages5
JournalCurrent Opinion in Immunology
Issue number2
StatePublished - Apr 1995
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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