Single T cell probes for antigen/MHC expression

Nilabh Shastri

doi:10.1016/0952-7915(95)80012-3

Single T cell probes for antigen/MHC expression

Nilabh Shastri

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

T-cell receptor binding to the antigen/MHC ligand on the surface of antigen-presenting cells is the central event in T-cell activation. Methods have been developed for measuring this recognition event in single T cells and have allowed their use as 'probes' for antigen/MHC expression. Single cell assays have allowed analysis of early events in T-cell activation, and of unknown ligands recognized by the T-cell receptor.

Original language	English (US)
Pages (from-to)	258-262
Number of pages	5
Journal	Current Opinion in Immunology
Volume	7
Issue number	2
DOIs	https://doi.org/10.1016/0952-7915(95)80012-3
State	Published - Apr 1995
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1016/0952-7915(95)80012-3

Cite this

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title = "Single T cell probes for antigen/MHC expression",

abstract = "T-cell receptor binding to the antigen/MHC ligand on the surface of antigen-presenting cells is the central event in T-cell activation. Methods have been developed for measuring this recognition event in single T cells and have allowed their use as 'probes' for antigen/MHC expression. Single cell assays have allowed analysis of early events in T-cell activation, and of unknown ligands recognized by the T-cell receptor.",

author = "Nilabh Shastri",

note = "Funding Information: author's laboratory is funded by grants from the NIH and the UC Tobacco Disease Related Research Program.",

year = "1995",

month = apr,

doi = "10.1016/0952-7915(95)80012-3",

language = "English (US)",

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pages = "258--262",

journal = "Current Opinion in Immunology",

issn = "0952-7915",

publisher = "Elsevier Limited",

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T1 - Single T cell probes for antigen/MHC expression

AU - Shastri, Nilabh

N1 - Funding Information: author's laboratory is funded by grants from the NIH and the UC Tobacco Disease Related Research Program.

PY - 1995/4

Y1 - 1995/4

N2 - T-cell receptor binding to the antigen/MHC ligand on the surface of antigen-presenting cells is the central event in T-cell activation. Methods have been developed for measuring this recognition event in single T cells and have allowed their use as 'probes' for antigen/MHC expression. Single cell assays have allowed analysis of early events in T-cell activation, and of unknown ligands recognized by the T-cell receptor.

AB - T-cell receptor binding to the antigen/MHC ligand on the surface of antigen-presenting cells is the central event in T-cell activation. Methods have been developed for measuring this recognition event in single T cells and have allowed their use as 'probes' for antigen/MHC expression. Single cell assays have allowed analysis of early events in T-cell activation, and of unknown ligands recognized by the T-cell receptor.

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U2 - 10.1016/0952-7915(95)80012-3

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M3 - Article

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AN - SCOPUS:0029029037

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SP - 258

EP - 262

JO - Current Opinion in Immunology

JF - Current Opinion in Immunology

IS - 2

ER -

Single T cell probes for antigen/MHC expression

Abstract

ASJC Scopus subject areas

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