Single-breathhold four-dimensional assessment of left ventricular morphological and functional parameters by magnetic resonance imaging using the VAST technique

Carlos Eduardo Rochitte, Clerio F. Azevedo, Miguel A. Rosário, Maria H R Siqueira, Victor Monsão, Manoj Saranathan, Thomas K. Foo, Roberto Kalil Filho, Giovanni G. Cerri, José A F Ramires

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: The accurate and reproducible assessment of cardiac volumes, function, and mass is of paramount importance in cardiology. In the present study we sought to determine whether the 3D cine-magnetic resonance (MR) technique, using the variable asymmetric sampling in time (VAST) approach, provided an accurate assessment of LV functional parameters when compared with the conventional 2D cine-MR technique. Methods: A total of 43 consecutive patients referred for a CMR examination for clinical reasons and 14 healthy volunteers were included in the study. Cine images were acquired using a steady-state free precession pulse sequence. Two different multiphase acquisitions were performed: conventional 2D cine-MR and 3D cine-MR. The short-axis cine images acquired by both cine-MR techniques were used for the quantitative assessment of LV end-diastolic, end-systolic and stroke volumes, LV mass and ejection fraction. Results: All CMR examinations were completed successfully, with both cine-MR imaging techniques yielding interpretable diagnostic results in all patients. Regarding the quantitative assessment, Bland-Altman analyses demonstrated a good agreement between the measurements of both cine-MR techniques for all LV parameters. In addition, the agreement between 2D and 3D cine-MR techniques for the qualitative assessment of LV global function was perfect (kappa = 1.0, P

Original languageEnglish (US)
Pages (from-to)90-98
Number of pages9
JournalOpen Cardiovascular Medicine Journal
Volume5
Issue number1
DOIs
StatePublished - 2011
Externally publishedYes

Keywords

  • Cine imaging
  • Fast imaging
  • Left ventricular function
  • Magnetic resonance imaging
  • Steady-state free precession
  • Three-dimensional

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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