Simulation of ventricular fibrillation in a 3-dimensional model of heart

Lawrence Eisenman, Nitish Thakor

Research output: Contribution to conferencePaperpeer-review

Abstract

A 3-D model is reconstructed from an isolated dog heart and discretized into 1473 elements. By incorporating the details of activation of nearest neighbors, velocity of propagation, and refractoriness of previously excited tissue, electrical propagation in normal heart is simulated. Excitation by six to ten extrastimuli results in a self-sustaining random activity considered equivalent of ventricular fibrillation (VF). This model reproduces some known experimental observations and predicts induction of VF by recurrent excitation and dispersion of refractory states in cardiac elements.

Original languageEnglish (US)
Pages181-182
Number of pages2
StatePublished - Nov 1 1988
EventProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society - New Orleans, LA, USA
Duration: Nov 4 1988Nov 7 1988

Other

OtherProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityNew Orleans, LA, USA
Period11/4/8811/7/88

ASJC Scopus subject areas

  • Engineering(all)

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