Simulating place field dynamics using spike timing-dependent plasticity

X. Yu, J. J. Knierim, I. Lee, H. Z. Shouval

Research output: Contribution to journalArticle

Abstract

Spatial firing fields (place fields) of rat hippocampal cells undergo changes when the rat runs stereotyped routes. Previously, Mehta et al. [Experience-dependent asymmetric shape of hippocampal receptive fields, Neuron 25 (2000) 700-715] indicated that spike timing-dependent plasticity (STDP) might explain the observed shift of the place field center of mass and the development of skewness. In this study, by using simulations of spiking neurons with STDP, we demonstrate that STDP may cause a shift and negative skewness in the synaptic weights vector; however, we explain why these changes do not necessarily result in negative skewness of place fields. We further explore the parameters and additional mechanisms that favor the development of skewness.

Original languageEnglish (US)
Pages (from-to)1253-1259
Number of pages7
JournalNeurocomputing
Volume69
Issue number10-12
DOIs
StatePublished - May 1 2006
Externally publishedYes

Keywords

  • Backward shift
  • Hippocampus model
  • Place cell
  • STDP
  • Skewness

ASJC Scopus subject areas

  • Computer Science Applications
  • Cognitive Neuroscience
  • Artificial Intelligence

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