Simplification of the research diagnosis of HIV-associated sensory neuropathy

Scott R. Evans; David B. Clifford; Douglas W. Kitch; Karl Goodkin; Giovanni Schifitto; Justin C. McArthur; David M. Simpson

doi:10.1310/hct0906-434

Simplification of the research diagnosis of HIV-associated sensory neuropathy

Scott R. Evans, David B. Clifford, Douglas W. Kitch, Karl Goodkin, Giovanni Schifitto, Justin C. McArthur, David M. Simpson

School of Medicine

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Peripheral neuropathy (PN) is the most common neurological complication of HIV infection, affecting over one third of patients. The research diagnosis of PN is complicated by the need for expensive, time-consuming, and noxious diagnostic tests. We investigated whether nerve conduction studies (NSC) and quantitative sensory tests (QST) provide added value for the diagnosis of PN for research purposes or whether the easily obtainable clinical measures (sensory and motor symptoms, sensitivity to pain and vibration, tendon reflexes, motor function) are sufficient.

Original language	English (US)
Pages (from-to)	434-439
Number of pages	6
Journal	HIV Clinical Trials
Volume	9
Issue number	6
DOIs	https://doi.org/10.1310/hct0906-434
State	Published - Nov 2008

Keywords

Nerve conduction
Peripheral neuropathy
Quantitative tests
Sensory nuropathy

ASJC Scopus subject areas

Infectious Diseases
Pharmacology (medical)

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10.1310/hct0906-434

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AU - Goodkin, Karl

AU - Schifitto, Giovanni

AU - McArthur, Justin C.

AU - Simpson, David M.

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AB - Peripheral neuropathy (PN) is the most common neurological complication of HIV infection, affecting over one third of patients. The research diagnosis of PN is complicated by the need for expensive, time-consuming, and noxious diagnostic tests. We investigated whether nerve conduction studies (NSC) and quantitative sensory tests (QST) provide added value for the diagnosis of PN for research purposes or whether the easily obtainable clinical measures (sensory and motor symptoms, sensitivity to pain and vibration, tendon reflexes, motor function) are sufficient.

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KW - Peripheral neuropathy

KW - Quantitative tests

KW - Sensory nuropathy

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Simplification of the research diagnosis of HIV-associated sensory neuropathy

Abstract

Keywords

ASJC Scopus subject areas

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