Simplification of the research diagnosis of HIV-associated sensory neuropathy

Scott R. Evans, David B. Clifford, Douglas W. Kitch, Karl Goodkin, Giovanni Schifitto, Justin C. McArthur, David M. Simpson

Research output: Contribution to journalArticle

Abstract

Peripheral neuropathy (PN) is the most common neurological complication of HIV infection, affecting over one third of patients. The research diagnosis of PN is complicated by the need for expensive, time-consuming, and noxious diagnostic tests. We investigated whether nerve conduction studies (NSC) and quantitative sensory tests (QST) provide added value for the diagnosis of PN for research purposes or whether the easily obtainable clinical measures (sensory and motor symptoms, sensitivity to pain and vibration, tendon reflexes, motor function) are sufficient.

Original languageEnglish (US)
Pages (from-to)434-439
Number of pages6
JournalHIV Clinical Trials
Volume9
Issue number6
DOIs
StatePublished - Nov 2008

Keywords

  • Nerve conduction
  • Peripheral neuropathy
  • Quantitative tests
  • Sensory nuropathy

ASJC Scopus subject areas

  • Infectious Diseases
  • Pharmacology (medical)

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  • Cite this

    Evans, S. R., Clifford, D. B., Kitch, D. W., Goodkin, K., Schifitto, G., McArthur, J. C., & Simpson, D. M. (2008). Simplification of the research diagnosis of HIV-associated sensory neuropathy. HIV Clinical Trials, 9(6), 434-439. https://doi.org/10.1310/hct0906-434