Similarity of DNA fingerprints due to chance and relatedness

C. C. Li, B. E. Weeks, A. Chakravarti

Research output: Contribution to journalArticlepeer-review

Abstract

Given the DNA fingerprints of two individuals with some bands being shared by both individuals, we define a new measure of the degree of similarity between the DNA profiles of two individuals. We use this measure to calculate the expected DNA similarity of two unrelated individuals of a randomly mating population; this similarity is due to chance only. Then, the expected similarity between two related individuals is obtained; this similarity is due to chance and relatedness. From these results, the degree of similarity due to relatedness alone may be calculated.

Original languageEnglish (US)
Pages (from-to)45-52
Number of pages8
JournalHuman Heredity
Volume43
Issue number1
DOIs
StatePublished - Jan 1 1993

Keywords

  • Coefficient of relationship
  • DNA fingerprints
  • Population genetics
  • Relatedness

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

Fingerprint Dive into the research topics of 'Similarity of DNA fingerprints due to chance and relatedness'. Together they form a unique fingerprint.

Cite this