Similarity analysis of bone mineral density measurements of femur sites using dendrogram

Ray R. Hashemi, Alexander A. Tyler, Chris Childers, Arthur Chausmer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Bone mineral density (BMD) measurements are the gold standard by which osteoporosis is diagnosed. Dual Energy X-ray Absorptiometry (DEXA) is the most commonly used measuring technique to assess BMD at both the hip and spine. There are three sites within each hip, collectively called the femoral sites, which are assessed - the femoral neck site, the trochanteric site, and Ward's triangle. It is a known fact that the different areas of the femur are composed of different percentages of cancellous bone. The null hypothesis that we examine in this paper is that there is no difference between the mineralization states at all of these sites. To do so, we introduce and present a dendrogram-based methodology that (1) identifies valid clusters for any two given subsets of the six sites, (2) uses the valid clusters to examine the existence of associations between the two subsets, and (3) the existence of association, if any, is measured by the degree of similarity between the two subsets. The obtained results in this research effort partially reject the null hypothesis.

Original languageEnglish (US)
Title of host publicationProceedings - Third International Conference onInformation Technology
Subtitle of host publicationNew Generations, ITNG 2006
Pages625-630
Number of pages6
DOIs
StatePublished - Nov 14 2006
EventThird International Conference on Information Technology: New Generations, ITNG 2006 - Las Vegas, NV, United States
Duration: Apr 10 2006Apr 12 2006

Publication series

NameProceedings - Third International Conference onInformation Technology: New Generations, ITNG 2006
Volume2006

Other

OtherThird International Conference on Information Technology: New Generations, ITNG 2006
CountryUnited States
CityLas Vegas, NV
Period4/10/064/12/06

Keywords

  • Bone mineral density
  • Degree of similarity
  • Dendrogram
  • Dual energy X-ray absorptiometry
  • Similarity analysis
  • Valid dendrogram

ASJC Scopus subject areas

  • Engineering(all)

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