Silencing the Cochlear Amplifier by Immobilizing Prestin

Ulrich Müller, Peter Gillespie

Research output: Contribution to journalShort survey


Achieving the exquisite sensitivity and frequency selectivity of the mammalian ear requires active amplification of input sound. In this issue of Neuron, Dallos and colleagues demonstrate that the molecular motor prestin, which drives shape changes in the soma of mechanosensory hair cells, underlies mechanical feedback mechanisms for sound amplification in mammals.

Original languageEnglish (US)
Pages (from-to)299-301
Number of pages3
Issue number3
StatePublished - May 8 2008
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)

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