Significance of leukocytosis after cardiac device implantation

Christine Tompkins, Alan Cheng, Jeffrey A Brinker, Joseph Marine, Saman Nazarian, David D Spragg, Sunil Sinha, Henry R Halperin, Gordon F. Tomaselli, Ronald D Berger, Hugh Calkins, Charles A. Henrikson

Research output: Contribution to journalArticle


Infection remains a feared complication after cardiac device implantation. Whether early postprocedural leukocytosis, a recognized marker of infection, is an indicator of impending infection is unclear and was the focus of this study. A retrospective chart review of consecutive patients who underwent implantable cardioverter defibrillator or pacemaker implantation was performed. The association between change in white blood cell (WBC) count and development of infection after device implantation was assessed. Infection was defined as pocket or lead infection or as bacteremia or sepsis 15,000/μl. Subjects with significant leukocytosis were younger (mean age 61.9 ± 16.5 vs 65.6 ± 15.1 years, p

Original languageEnglish (US)
Pages (from-to)1608-1612
Number of pages5
JournalThe American Journal of Cardiology
Issue number11
StatePublished - Jun 1 2013


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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