Significance of basal follicle-stimulating hormone levels in women with one ovary in a program of in vitro fertilization

E. Khalifa, J. P. Toner, S. J. Muasher, A. A. Acosta

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To understand the impact of having a single ovary on basal follicle-stimulating hormone (FSH) level and its diagnostic and prognostic usefulness in in vitro fertilization (IVF). Design: All IVF cases from July 1987 to June 1990 with known basal FSH (n = 1,272) were divided into those with one and those with two ovaries to compare outcomes based on basal FSH levels. Setting: Tertiary care academic center with a large IVF practice. Main Outcome Measures: Basal FSH, age, and IVF outcomes including peak estradiol, numbers of follicles aspirated, oocytes retrieved, fertilized, and transferred, and pregnancies (clinical and ongoing). Results: In women with only one ovary, basal FSH was increased, and IVF outcomes were poorer. The rise in FSH was able, in large part, to account for the diminished performance in the single ovary cases. Conclusions: Women with only one ovary have higher basal FSH levels than those with two ovaries, and this rise can be used to predict their IVF performance.

Original languageEnglish (US)
Pages (from-to)835-839
Number of pages5
JournalFertility and sterility
Volume57
Issue number4
DOIs
StatePublished - 1992

Keywords

  • Ovary
  • basal follicle-stimulating hormone/in vitro fertilization
  • oophorectomy

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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