Signaling by gasotransmitters

Asif K. Mustafa, Moataz M. Gadalla, Solomon H. Snyder

Research output: Contribution to journalReview article

Abstract

Nitric oxide is well established as a major signaling molecule. Evidence is accumulating that carbon monoxide and hydrogen sulfide also are physiologic mediators in the cardiovascular, immune, and nervous systems. This Review focuses on mechanisms whereby they signalby binding to metal centers in metalloproteins, such as in guanylyl cyclase, or modifyingsulfhydryl groups in protein targets.

Original languageEnglish (US)
Pages (from-to)re2
JournalScience signaling
Volume2
Issue number68
DOIs
StatePublished - Apr 28 2009

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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