TY - JOUR
T1 - Shrinking patches and slippery rafts
T2 - Scales of domains in the plasma membrane
AU - Edidin, Michael
PY - 2001/12/1
Y1 - 2001/12/1
N2 - Many types of experiment show that the plasma membranes of cells are patchy and locally differentiated into domains. Some of these domains seem to arise through the confinement of diffusible membrane proteins. Others might arise through lipid-lipid interactions. Both types of domain are transient on a biological timescale but both could create local conditions that enhance molecular interactions, such as those that occur in receptor-mediated signaling.
AB - Many types of experiment show that the plasma membranes of cells are patchy and locally differentiated into domains. Some of these domains seem to arise through the confinement of diffusible membrane proteins. Others might arise through lipid-lipid interactions. Both types of domain are transient on a biological timescale but both could create local conditions that enhance molecular interactions, such as those that occur in receptor-mediated signaling.
UR - http://www.scopus.com/inward/record.url?scp=0035575575&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035575575&partnerID=8YFLogxK
U2 - 10.1016/S0962-8924(01)02139-0
DO - 10.1016/S0962-8924(01)02139-0
M3 - Review article
C2 - 11719055
AN - SCOPUS:0035575575
VL - 11
SP - 492
EP - 496
JO - Trends in Cell Biology
JF - Trends in Cell Biology
SN - 0962-8924
IS - 12
ER -