Short-term variablility of respiration and sleep during unattended nonlaboratory polysomnogaphy - The sleep heart health study

Stuart F. Quan, Michael E. Griswold, Conrad Iber, F. Javier Nieto, David M. Rapoport, Susan Redline, Mark Sanders, Terry Young

Research output: Contribution to journalArticle

Abstract

Study Objectives: To determine the short-term variability of indices of disturbed respiration and sleep during 2 nights of unattended nonlaboratory polysomnography conducted several months apart. Design: Participants were randomly selected using a block design with stratification on preliminary estimates of 2 criteria: respiratory disturbance index [RDI3% (apnea or hypopnea events associated with ≥3% O2 desaturation): 3% and RDI4% (apnea or hypopnea events associated with ≥4% O2 desaturation). Variability between studies estimated using intraclass correlations (ICC) ranged from 0.77 to 0.81. For subjects with a RDI3% ≥15, variability increased as a function of increasing RDI, but for those with a RDI3%≥15, variability was constant. Body mass index, SEff, gender, or age did not directly predict RDI variability. Using RDI4% cutpoints of ≤5, ≤10 and ≤15 events per hour of sleep demonstrated that 79.1%, 85.7%, and 87.9% of subjects, respectively, had the same classification of SDB status on both nights of study. There also was no significant bias in sleep staging, sleep efficiency, or arousal index between studies. However, variability was greater with ICC values ranging from 0.37 (% time in REM) to 0.76 (arousal index). Conclusion: In the Sleep Heart Health Study, accurate estimates of the severity of sleep-disordered breathing and the quality of sleep were obtained from a single night of unattended nonlaboratory polysomnography. These findings may be applicable to other large epidemiologic studies provided that similar recording techniques and quality-assurance procedures are followed.

Original languageEnglish (US)
Pages (from-to)843-849
Number of pages7
JournalSleep
Volume25
Issue number8
StatePublished - Dec 15 2002

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Sleep
Respiration
Health
Polysomnography
Apnea
Arousal
Sleep Apnea Syndromes
Epidemiologic Studies
Body Mass Index

Keywords

  • Apnea
  • Hypopnea
  • Polysomnography
  • Reproducibility
  • Sleep-disordered breathing
  • Variability

ASJC Scopus subject areas

  • Physiology

Cite this

Quan, S. F., Griswold, M. E., Iber, C., Javier Nieto, F., Rapoport, D. M., Redline, S., ... Young, T. (2002). Short-term variablility of respiration and sleep during unattended nonlaboratory polysomnogaphy - The sleep heart health study. Sleep, 25(8), 843-849.

Short-term variablility of respiration and sleep during unattended nonlaboratory polysomnogaphy - The sleep heart health study. / Quan, Stuart F.; Griswold, Michael E.; Iber, Conrad; Javier Nieto, F.; Rapoport, David M.; Redline, Susan; Sanders, Mark; Young, Terry.

In: Sleep, Vol. 25, No. 8, 15.12.2002, p. 843-849.

Research output: Contribution to journalArticle

Quan, SF, Griswold, ME, Iber, C, Javier Nieto, F, Rapoport, DM, Redline, S, Sanders, M & Young, T 2002, 'Short-term variablility of respiration and sleep during unattended nonlaboratory polysomnogaphy - The sleep heart health study', Sleep, vol. 25, no. 8, pp. 843-849.
Quan SF, Griswold ME, Iber C, Javier Nieto F, Rapoport DM, Redline S et al. Short-term variablility of respiration and sleep during unattended nonlaboratory polysomnogaphy - The sleep heart health study. Sleep. 2002 Dec 15;25(8):843-849.
Quan, Stuart F. ; Griswold, Michael E. ; Iber, Conrad ; Javier Nieto, F. ; Rapoport, David M. ; Redline, Susan ; Sanders, Mark ; Young, Terry. / Short-term variablility of respiration and sleep during unattended nonlaboratory polysomnogaphy - The sleep heart health study. In: Sleep. 2002 ; Vol. 25, No. 8. pp. 843-849.
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abstract = "Study Objectives: To determine the short-term variability of indices of disturbed respiration and sleep during 2 nights of unattended nonlaboratory polysomnography conducted several months apart. Design: Participants were randomly selected using a block design with stratification on preliminary estimates of 2 criteria: respiratory disturbance index [RDI3{\%} (apnea or hypopnea events associated with ≥3{\%} O2 desaturation): 3{\%} and RDI4{\%} (apnea or hypopnea events associated with ≥4{\%} O2 desaturation). Variability between studies estimated using intraclass correlations (ICC) ranged from 0.77 to 0.81. For subjects with a RDI3{\%} ≥15, variability increased as a function of increasing RDI, but for those with a RDI3{\%}≥15, variability was constant. Body mass index, SEff, gender, or age did not directly predict RDI variability. Using RDI4{\%} cutpoints of ≤5, ≤10 and ≤15 events per hour of sleep demonstrated that 79.1{\%}, 85.7{\%}, and 87.9{\%} of subjects, respectively, had the same classification of SDB status on both nights of study. There also was no significant bias in sleep staging, sleep efficiency, or arousal index between studies. However, variability was greater with ICC values ranging from 0.37 ({\%} time in REM) to 0.76 (arousal index). Conclusion: In the Sleep Heart Health Study, accurate estimates of the severity of sleep-disordered breathing and the quality of sleep were obtained from a single night of unattended nonlaboratory polysomnography. These findings may be applicable to other large epidemiologic studies provided that similar recording techniques and quality-assurance procedures are followed.",
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