Short-term blood pressure regulation: A combination of feedback and mechanics

J. Philip Saul, Ronald D. Berger, Richard J. Cohen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Experimental results from the use of nonparametric transfer function analysis in combination with broadband respiration to compute the magnitude and phase relations between respiration, heart rate (HR), and arterial blood pressure (ABP) have led to formulation of a model of HR and ABP control which includes the mechanical feedforward from HR to ABP, the baroreflex feedback from ABP to HR, and respiration as a noise source which directly affects HR via central modulation of autonomic activity and affects ABP via mechanical thoracic coupling. Combining results from the model with experimental observations, it is concluded that short-term ABP variability results from a combination of mechanical and autonomic influences, where the precise mixture depends on an individual's autonomic state.

Original languageEnglish (US)
Title of host publicationBiomedical Engineering Perspectives
Subtitle of host publicationHealth Care Technologies for the 1990's and Beyond
PublisherPubl by IEEE
Number of pages1
Editionpt 2
ISBN (Print)0879425598
StatePublished - Dec 1 1990
Externally publishedYes
EventProceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Philadelphia, PA, USA
Duration: Nov 1 1990Nov 4 1990

Publication series

NameProceedings of the Annual Conference on Engineering in Medicine and Biology
Numberpt 2
ISSN (Print)0589-1019

Other

OtherProceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityPhiladelphia, PA, USA
Period11/1/9011/4/90

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ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Saul, J. P., Berger, R. D., & Cohen, R. J. (1990). Short-term blood pressure regulation: A combination of feedback and mechanics. In Biomedical Engineering Perspectives: Health Care Technologies for the 1990's and Beyond (pt 2 ed.). (Proceedings of the Annual Conference on Engineering in Medicine and Biology; No. pt 2). Publ by IEEE.