Short communication: Fracture risk by HIV infection status in perinatally HIV-exposed children

George K. Siberry, Hong Li, Denise Jacobson

Research output: Contribution to journalArticlepeer-review

Abstract

The objective of this study was to examine the incidence of fractures in HIV-infected children and comparable HIV-exposed, uninfected (HEU) children in a multicenter, prospective cohort study (PACTG 219/219C) in the United States. The main outcome was first fracture during the risk period. Nine fractures occurred in 7 of 1326 HIV-infected and 2 of 649 HEU children, corresponding to incidence rates of 1.2 per 1000 person-years and 1.1 per 1000 person-years, respectively. The incidence rate ratio was 1.1 (95% CI 0.2, 5.5). There was no evidence of a substantially increased risk of fracture in HIV-infected compared to HEU children.

Original languageEnglish (US)
Pages (from-to)247-250
Number of pages4
JournalAIDS research and human retroviruses
Volume28
Issue number3
DOIs
StatePublished - Mar 1 2012

ASJC Scopus subject areas

  • Immunology
  • Virology
  • Infectious Diseases

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