Sezary cells in ascitic fluid

S. E. Vernon, D. L. Rosenthal

Research output: Contribution to journalArticle

Abstract

Sezary's syndrome is a neoplasm of T-lymphocytes characterized by skin lesions histologically typical of mycosis fungoides together with the presence of malignant (Sezary) cells in the peripheral blood. These cells have a characteristic appearance in tissues, peripheral blood and body fluids, and their presence in large numbers in ascitic fluid is an indicator of disseminated disease. A patient with Sezary's syndrome was found to have the distinctive malignant lymphocytes in ascitic fluid. We believe that this report is the first to document the appearance of the cells in a body cavity fluid. Treatment modalities in Sezary's syndrome may be determined by the stage of the disease, and the presence of the distinctive 'convoluted' or 'cerebreform' lymphocytes should be noted.

Original languageEnglish (US)
Pages (from-to)408-411
Number of pages4
JournalActa cytologica
Volume23
Issue number5
StatePublished - Jan 1 1979

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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