Sexual partner characteristics and incident rectal Neisseria gonorrhoeae and Chlamydia trachomatis infections among gay men and other men who have sex with men (MSM): A prospective cohort in Abuja and Lagos, Nigeria

Habib O. Ramadhani, Hongjie Liu, Rebecca G. Nowak, Trevor A. Crowell, Teclaire Ndomb, Charlotte Gaydos, Sheila Peel, Nicaise Ndembi, Stefan D. Baral, Julie Ake, Man E. Charurat

Research output: Contribution to journalArticlepeer-review

Abstract

Background STIs including Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) potentiate HIV acquisition and transmission especially among gay men and other men who have sex with men (MSM). We investigated the influence of sexual network composition on incident rectal NG and/or CT infections among Nigerian MSM. Methods TRUST/RV368 is a cohort of MSM recruited using respondent-driven sampling at trusted community centres in Abuja and Lagos, Nigeria. MSM respondents (egos) provided STI risk factors and demographic information for up to five of their most recent sexual partners (alters) within their sexual networks. Egos were tested for HIV, NG and CT every 3months. Log-binomial regression was used to assess associations between alter characteristics and incident NG and/or CT. Results Between March 2013 and October 2015, 492 MSM were longitudinally screened for STIs, of which 28.0% (n=138) were positive for incident rectal STI (61 NG only, 42 CT only and 35 NG and CT). Among egos, condom use was associated with STIs (half of the time vs never (adjusted risk ratio (aRR) 0.5; 95% CI 0.3 to 0.8), always/almost always vs never (aRR 0.7; 95% CI 0.5 to 1.0)). Incident STIs were associated with having a younger alter ≤19 versus 30years (aRR 0.6; 95% CI 0.4 to 1.0), HIV infection (aRR 1.5; 95% CI 1.1 to 2.0) and engaging in sex under the influence of alcohol (aRR 1.4 95% CI 1.1 to 1.7) among regular alters and age ≤19 versus 30years (aRR 0.3; 95% CI 0.2 to 0.6), HIV infection (aRR 1.4; 95% CI 1.1 to 1.8) and engaging in sex under the influence of alcohol (aRR 1.2 95% CI 1.0 to 1.4) among casual alters. Conclusions Given the centrality of sexual partner characteristics as risks for incident STIs among Nigerian MSM, there is a need to move beyond individual interventions and syndromic surveillance and get out there' in the STI management.

Original languageEnglish (US)
Pages (from-to)348-355
Number of pages8
JournalSexually transmitted infections
Volume93
Issue number5
DOIs
StatePublished - Aug 1 2017

Keywords

  • CHLAMYDiA TRACHOMATIS
  • GAY MEN
  • HOMOSEXUALITY
  • NEISSERIA GONORRHOEA
  • SEXUAL NETWORKS

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases

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